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Análisis de la expresión del complejo inflamasoma (NALP3, ASC y CASPASA-1) en ojo de ratón
(15/12/2010)
ABSTRACT: The early stages of the response to infection depend on innate immunity that uses different mechanisms to recognize and respond to the presence of a pathogen. The cells of the innate immune system produce potent ...
HIV-1 induces NALP3-inflammasome expression and interleukin-1 beta secretion in dendritic cells from healthy individuals but not from HIV-positive patients
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
Objective: NALP3-inflammasome is an innate mechanism, alternative to type-1 interferon, which is able to recognize nucleic acids and viruses in the cytoplasm and to induce pro-inflammatory response. Here, we hypothesized ...
Polymorphisms in Inflammasome' Genes and Susceptibility to HIV-1 Infection
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
The involvement of inflammasome genes in the susceptibility to HIV-1 infection was investigated. Twelve single nucleotide polymorphisms within NLRP1, NLRP3, NLRC4, CARD8, CASP1, and IL1B genes were analyzed in 150 ...
El inflamasoma: mecanismos de activación.
(Universidad del Zulia, 2015)
Genetic polymorphism in an inflammasome component, cervical mycoplasma detection and female infertility in women undergoing in vitro fertilization
(ELSEVIER IRELAND LTD, 2010)
The inflammasome is an inducible cytoplasmic structure that is responsible for production and release of biologically active interleukin-1 (IL-1). A polymorphism in the inflammasome component NALP3 has been associated with ...
El papel de la map cinasa p38 en la regulación del inflamasoma en macrófagos susceptibles y resistentes a la toxina letal de bacillus anthracis
(2012-06-14)
RESUMEN: inflamasoma es un complejo multiprotéico que controla la activación de Caspasa-1 y la producción de citocinas pro-inflamatorias en respuesta a diferentes componentes de agentes patógenos o a componentes intracelulares ...