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Synergy of DNA-bending nucleoid proteins and macromolecular crowding in condensing DNA
(2007-10-01)
Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...
Synergy of DNA-bending nucleoid proteins and macromolecular crowding in condensing DNA
(2007-10-01)
Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...
Electrochemical nucleic acid biosensors for the detection of interaction between peroxynitrite and DNA
(WILEY-V C H VERLAG GMBH, 2007-07)
We studied the reactivity of peroxynitrite and different nucleic acid molecules using DNA electrochemical biosensors. SIN-1 (3-morpholinosydnonimine) has been used for the simultaneous generation of NO- and superoxide, ...
Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi
(Nature Research, 2019)
Antitumour Complexes and DNA Interactions and their Tools of Analysis: an Approach to Metalointercalators
(Brazilian Chemical Soc, 2015-11-01)
DNA is considered to be one of the major targets of anticancer drugs. Cisplatin and its analogues exert their activity by forming covalent bonds with the DNA base pairs. However, the DNA structure enables its interaction ...
In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization
(Royal Soc Chemistry, 2011-01-01)
An in situ evaluation of the dsDNA-methotrexate (MTX) interaction was performed by voltammetry using a DNA-electrochemical biosensor and characterized by atomic force microscopy (AFM) at a highly oriented pyrolytic graphite ...
In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization
(Royal Soc Chemistry, 2011-01-01)
An in situ evaluation of the dsDNA-methotrexate (MTX) interaction was performed by voltammetry using a DNA-electrochemical biosensor and characterized by atomic force microscopy (AFM) at a highly oriented pyrolytic graphite ...
Electrochemical investigations on the capacity of flavonoids to protect DNA against damage caused by textile disperse dyes
(Elsevier B.V., 2014-03-01)
In previous work, the interaction of DNA with the textile dyes Disperse Orange 1 (DO1) and Disperse Red 1 (DR1), and their electrolysis products, resulted in significant changes in the characteristic oxidation peaks of the ...