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Synthesis and acetylcholinesterase inhibitory activity of polyhydroxylated sulfated steroids: structure/activity studies
(Elsevier, 2013-08)
Disulfated and trisulfated steroids have been synthesized from cholesterol and their acetylcholinesterase inhibitory activity has been evaluated. In our studies we have found that the activity was not only dependent on the ...
Antioxidants, quinone reductase inducers and acetylcholinesterase inhibitors from Spondias tuberosa fruits
(2016-03-01)
The methanolic extract of umbu (Spondias tuberosa) presented high antioxidant activities in the DPPH, ABTS and ORAC assays, as well as acetylcholinesterase (AChE) inhibition activity. The dichloromethane extract exhibited ...
New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids
(Elsevier B.V., 2005-07-01)
Five new piperidine alkaloids were designed from natural (-)-3-O-acetyl-spectaline and (-)-spectaline that were obtained from the flowers of Senna spectabilis (sin. Cassia spectabilis, Leguminosae). Two semi-synthetic ...
Synthesis of tricyclic analogs of stephaoxocanidine and their evaluation as acetylcholinesterase inhibitors
(Pergamon-Elsevier Science Ltd., 2005)
The Electronic Influence on the Active Site-Directed Inhibition of
(Journal of the Mexican Chemical Society, 2013-01-16)
Antifungals and acetylcholinesterase inhibitors from the stem bark of Croton heliotropiifolius
(Elsevier B.V., 2014-12-01)
The ethanolic extract of the stem bark of Croton heliotropiifolius Kunth (Euphorbiaceae) showed significant in vitro inhibition of acetylcholinesterase using a dilution spectrophotometric assay and antifungal activity ...
Screening of acetylcholinesterase inhibitors in marine organisms from the Caribbean Sea
The acetylcholinesterase inhibitory activity of 89 organic extracts
from marine organisms was evaluated through a TLC bioautography
methodology. Extracts from soft corals (Eunicea and Plexaura) were
the most active ...