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Promiscuous subunit interactions: A possible mechanism for the regulation of protein kinase CK2
(1998)
Protein kinase CK2 is a ubiquitous eukaryotic ser/thr protein kinase. The active holoenzyme is a heterotetrameric protein corn posed of catalytic (α and α') and regulatory (β) subunits that phosphorylates many different ...
Folding kinetic pathway of phosphofructokinase-2 from Escherichia coli: A homodimeric enzyme with a complex domain organization
(2011)
Phosphofructokinase-2 is a 66 kD homodimer whose subunits are associated by means of a bimolecular domain, the β-clasp, which is linked to the larger portion of each subunit by a reentrant chain topology. To investigate ...
Chemical modification of SH groups of E. coli Phosphofructokinase-2 induces subunit dissociation: Monomers are inactive but preserve ligand binding properties
(Taylor & Francis, 2000)
Modification of Escherichia coli phosphofructokinase-2 (Pfk-2) with N- (1-pyrenil)maleimide results in an enzyme form that is inactive. However, the rate of modification is drastically reduced in the presence of the ...
The association of Na,K-ATPase subunits studied by circular dichroism, surface tension and dilatational elasticity
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
Different stoichiometries are observed between alpha and beta subunits of Na,K-ATPase that depend on the method employed to solubilize and purify the enzyme. It is not known whether this variability is due to loss of ...
An inactive mutant of the α subunit of protein kinuse CK2 that traps the regulatory CK2β subunit
(1997)
Protein kinase CK2 (casein kinase 2) is a ubiquitous Ser/Thr protein kinase involved in cell proliferation. Mutation of the α subunit of the Xenopus laevis CK2 to change aspartic acid 156 to alanine (CK2αA156) resulted in ...
Regulatory network of the allosteric ATP inhibition of E. coli phosphofructokinase-2 studied by hybrid dimers
(Elsevier B.V., 2016)
© 2016 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM) We have proposed an allosteric ATP inhibition mechanism of Pfk-2 determining the structure of different forms of the enzyme together ...
Oral cancer and cyclins (multiple letters)
(2004-07-01)
Oral cancer and cyclins (multiple letters)
(2004-07-01)
Mechanisms of Activation and Subunit Release in Ca 2+ /Calmodulin-Dependent Protein Kinase II
(American Chemical Society, 2017-11)
Calcium/calmodulin-dependent protein kinase II is an enzyme involved in many different functions, including the so-called long-term potentiation, a mechanism that strengthens synapses in a persistent mode and is believed ...