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Molecular implications of adenosine in obesity
(2017)
Adenosine has broad activities in organisms due to the existence of multiple receptors, the differential adenosine concentrations necessary to activate these receptors and the presence of proteins able to synthetize, degrade ...
Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels
(2017)
Adenosine as well as agonists and antagonists for the four adenosine receptor subtypes (A1R, A2AR, A2BR and A3R) play a role in several key physiological and pathophysiological processes, including the regulation of vascular ...
Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A(2B) adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia
(W B SAUNDERS CO LTD, 2008)
Pre-eclampsia is associated with elevated maternal blood pressure and proteinuria, altered fetal growth, and increased plasma adenosine concentration in the mother and the fetus. Human equilibrative nucleoside transporters ...
New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway
(Frontiers Research Foundation, 2015-03-25)
G protein coupled receptors (GPCRs) linked to stimulatory G (Gs) proteins (GsPCRs) mediate increases in intracellular cyclic AMP as consequence of activation of nine adenylyl cyclases, which differ considerably in their ...
Molecular implications of adenosine in obesity
(2017-06)
Adenosine has broad activities in organisms due to the existence of multiple receptors, the differential adenosine concentrations necessary to activate these receptors and the presence of proteins able to synthetize, degrade ...
Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training
(Blackwell Publishing Asia, 2004-10-01)
The aim of the present study was to evaluate the potency and maximal responses (E-max) to the adenosine receptor agonists N-6-cyclopentyladenosine (CPA), N-ethylcarboxamidoadenosine (NECA) and N-6-(3-iodobenzyl)-5'-N-met ...
Adenosine in the lateral hypothalamus/perifornical area does not participate on the CO2 chemoreflex
(2020-05-01)
The Lateral Hypothalamus/Perifornical Area (LH/PFA) has been shown to be involved with the hypercapnic ventilatory response, in a state-dependent manner. We have demonstrated that purinergic signaling through ATP in the ...