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Requirement for BDNF in the Reconsolidation of Fear Extinction
(2015-04-22)
Therapies based on the impairment of reconsolidation or the enhancement of extinction offer the possibility of decreasing the persistent recollection of distressing memories. However, the direct interplay between reconsolidation ...
Requirement for BDNF in the reconsolidation of fear extinction
(Society for Neuroscience, 2015-04)
Therapies based on the impairment of reconsolidation or the enhancement of extinction offer the possibility of decreasing the persistent recollection of distressing memories. However, the direct interplay between reconsolidation ...
A comparison of behavioral and pharmacological interventions to attenuate reactivated fear memories
(Cold Spring Harbor Lab Press, 2017-08)
Two experiments using rats in a contextual fear memory preparation compared two approaches to reduce conditioned fear: (1) pharmacological reconsolidation blockade and (2) reactivation-plus-extinction training. In Experiment ...
Disruptive effect of midazolam on fear memory reconsolidation: Decisive influence of reactivation time span and memory age
(Nature Publishing Group, 2009-01)
Benzodiazepine (BDZ) administered shortly after retrieval disrupts the reconsolidation of fear memory. In this research, we explored the way in which different factors that limit the emergence of such process may affect ...
Retrieval induces reconsolidation of fear extinction memory
(National Academy of Sciences, 2010-12)
The nonreinforced expression of long-tem memory may lead to two opposite protein synthesis-dependent processes: extinction and reconsolidation. Extinction weakens consolidated memories, whereas reconsolidation allows ...
Papel de mTOR, BDNF, AMPAR E NMDAR na reconsolidação da memória de extinção
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PSICOBIOLOGIA, 2019-03-15)
Memory reactivation can induce two apparently competing processes,
namely extinction and reconsolidation. Extinction involves reduction of a
previously acquired response to a stimulus through formation of a new memory
trace. ...
Reconsolidação da memória de extinção: análise farmacológica, bioquímica e molecular
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2015)
Background : Therapies based on the impairment of memory reconsolidation or the enhancement of extinction learning offer the possibility of diminishing the impact caused by the persistent recollection of traumatic events. ...
Reconsolidação da memória de extinção: análise farmacológica, bioquímica e molecular
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2015)
Background : Therapies based on the impairment of memory reconsolidation or the enhancement of extinction learning offer the possibility of diminishing the impact caused by the persistent recollection of traumatic events. ...
Mediational role of hormones in incentive contrast
(International Society for Comparative Psychology, 2014-08)
Frustration can be defined as an emotional state generated by the omission or devaluation in the quantity or quality of an expected appetitive reward. Thus, reactivity to a reward is affected by prior experience with the ...
On Disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment
(NATURE PUBLISHING GROUPLONDON, 2012)
The search for reconsolidation blockers may uncover clinically relevant drugs for disrupting memories of significant stressful life experiences, such as those underlying the posttraumatic stress disorder. Considering the ...