| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Saltzman, W. Mark | |
| dc.date | 2016-10-26T18:06:01Z | |
| dc.date | 2016-10-26T18:06:01Z | |
| dc.date.accessioned | 2017-04-06T12:54:27Z | |
| dc.date.available | 2017-04-06T12:54:27Z | |
| dc.identifier | http://acervodigital.unesp.br/handle/unesp/369622 | |
| dc.identifier | http://objetoseducacionais2.mec.gov.br/handle/mec/13306 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/965904 | |
| dc.description | Presents a class where Professor Saltzman reviews the pharmacokinetic first-order rate equation that can be used to model changes in drug concentration in the blood, as well as its derivation from the law of conservation of mass. The importance of maintaining a drug concentration that is sufficient for therapeutic purpose, but below a toxic level, is emphasized. Since this is directly affected by drug administration method, ways to localize and sustain therapeutic concentrations of drug, such as incorporating in slow-releasing, biocompatible polymers are introduced. Professor Saltzman gave some examples of clinical applications of controlled release drug delivery system, such as anti-restenosis drug incorporated into stents, and chemotherapeutic drugs in brain implants and microspheres | |
| dc.description | Educação Superior::Ciências da Saúde::Farmácia | |
| dc.description | Educação Superior::Engenharias::Engenharia Biomédica | |
| dc.publisher | Yale University, Open Yale Courses | |
| dc.relation | Biomolecular Engineering 4.mp3 | |
| dc.rights | Yale University 2009. Some rights reserved. Unless otherwise indicated in the applicable Credits section of certain lecture pages, all content on this web site is licensed under a Creative Commons License. Please refer to the Credits section to determine whether third-party restrictions on the use of content apply | |
| dc.subject | Educação Superior::Engenharias::Engenharia Biomédica::Engenharia Médica | |
| dc.subject | Educação Superior::Ciências da Saúde::Farmácia::Análise e Controle e Medicamentos | |
| dc.subject | Biomolecular engineering | |
| dc.subject | Pharmacokinetic | |
| dc.title | Biomolecular engineering: general concepts: part 2 [Frontiers of biomedical engineering] | |
| dc.type | Audios | |
