The effect of a Lactobacillus-based probiotic for the control of necrotic enteritis in broilers

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorLayton, Sherryll Lynn
dc.creatorHernandez-Velasco, Xochit
dc.creatorChaitanya, Shivaramaiah
dc.creatorXavier, Jorge
dc.creatorMenconi, Anita
dc.creatorLatorre, Juan David
dc.creatorKallapura, Gopala
dc.creatorKuttappan, Vivek Ayamchirakkunnel
dc.creatorWolfenden, Ross Elderon
dc.creatorAndreatti Filho, Raphael Lucio
dc.creatorHargis, Billy Marshal
dc.creatorTellez, Guillermo
dc.date2016-04-01T18:43:53Z
dc.date2016-10-25T21:36:25Z
dc.date2016-04-01T18:43:53Z
dc.date2016-10-25T21:36:25Z
dc.date2013
dc.date.accessioned2017-04-06T10:17:55Z
dc.date.available2017-04-06T10:17:55Z
dc.identifierFood and Nutrition Sciences, v. 4, n. 11, p. 1-7, 2013.
dc.identifier2157-9458
dc.identifierhttp://hdl.handle.net/11449/137038
dc.identifierhttp://acervodigital.unesp.br/handle/11449/137038
dc.identifier10.4236/fns.2013.411A001
dc.identifierISSN2157-9458-2013-04-11-01-07.pdf
dc.identifier8598014963221729
dc.identifierhttp://dx.doi.org/10.4236/fns.2013.411A001
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/947560
dc.descriptionNecrotic Enteritis (NE) caused by Clostridium perfringens (CP) in poultry is probably the most important bacterial disease in terms of economic implications. The disease is multi-factorial and is invariably associated with predisposing factors. The present study investigated the effect of a commercially available Lactobacillus-based probiotic (FM-B11) for the control of necrotic enteritis in broiler chickens. In experiment 1, one-day-of-hatch broiler chicks were randomly allocated to the following treatment groups: 1) Non-challenged (NC); 2) Challenged (C); 3) Challenged + probiotic (C+ FM-B11). Prior to placement, chicks in groups 2 and 3 received 0.25 mL of Salmonella typhimurium (ST) containing 105 cfu of viable cells by oral gavage. At 14, 15 and 16 days of age, all chicks in group 3 were treated with FM-B11 in the drinking water at a concentration of 106 cfu/ml. At 21d of age, all chicks in groups 2 and 3, were individually challenged with 5 × 104 sporulated oocysts of E. maxima by oral gavage. At 26d of age, all chicks in groups 2 and 3, were individually challenged with 108 cfu CP; body weight (BW) was recorded prior to challenge. The experiment was terminated at 29 days of age and the following parameters were evaluated: NE-associated mortality, CP lesion scores, CP concentrations in ileum, BW, and body weight gain (BWG). Chicks treated with FM-B11 had significantly (P < 0.05) higher body weight gain after challenge when compared to control challenge chickens. Total mortality was higher in the C group (48.8%) when compared to the C + FM-B11 (12.7%). Even though there was no significant (P > 0.05) difference in lesion score between C and C + FM-B11, group C + FM-B11 had significantly (P < 0.05) lower total number of cfu of CP recovered from the ileal mucosa and content samples when compared to group C. Experiment 2 was a unique and remarkable case report of a field outbreak of NE in a commercial broiler farm in Argentina. A reduction and control of the mortality associated with NE following 3 days of administration of FM-B11 was observed as compared with the control non treated house. These results imply that the commercially available Lactobacillus-based probiotic FM-B11 was able to reduce the severities of NE, as a secondary bacterial infection, in an experimental NE challenge model; as well as, in a commercial field outbreak of NE.
dc.languageeng
dc.relationFood and Nutrition Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLactobacillus
dc.subjectNecrotic enteritis
dc.subjectSalmonella
dc.subjectCoccidiosis
dc.subjectProbiotic
dc.titleThe effect of a Lactobacillus-based probiotic for the control of necrotic enteritis in broilers
dc.typeOtro


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