dc.contributorDel Valle Mendoza, Juana Mercedes
dc.creatorHerrera Alzamora, Angella
dc.creatorBendezú Medina, Sandy
dc.creatorPavic-Espinoza, Ivana
dc.date2017-08-21T16:10:15Z
dc.date2017-08-21T16:10:15Z
dc.date2017-08-21T16:10:15Z
dc.date2017-08-21T16:10:15Z
dc.date2016-01-25
dc.date.accessioned2024-05-15T16:15:57Z
dc.date.available2024-05-15T16:15:57Z
dc.identifierhttp://hdl.handle.net/10757/621806
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9420127
dc.descriptionBackground: Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate. Methods: A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses of acute respiratory infections were test for B. pertussis and RSV detection by polymerase chain reaction (PCR). Results: The pertussis toxin and IS481 genes were detected in 19.12% (114/596) of the cases and the respiratory syncytial viruses (RSV-A and RSV-B) were identified in 17.28% (103/596) of patients. Infants under 3 months old were the most frequently affected by this pathogens in 43% (49/114) and 35.9% (37/103) respectively. An increase of B. pertussis was observed from February to March and from October to November with a Seasonal index between 1.32-1.51 and 1.24-3.5 respectively. Conclusions: Epidemiologic surveillance for B. pertussis is essential in Peru, especially in children that could most benefit from the vaccine. B. pertussis should be suspected in infants hospitalized for acute respiratory symptoms for early treatment and prevent complications.
dc.descriptionTesis
dc.formatapplication/pdf
dc.formatapplication/msword
dc.languageeng
dc.publisherUniversidad Peruana de Ciencias Aplicadas (UPC)
dc.publisherPE
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)
dc.sourceRepositorio Académico - UPC
dc.subjectInfants
dc.subjectVaccine
dc.subjectBronchiolitis
dc.subjectBordetella pertussis
dc.titlePrevalencia y factores asociados a infección por Bordetella Pertussis en niños menores de 5 años con infección respiratoria aguda (IRA) en un hospital de Lima
dc.typeTesis
dc.typeinfo:eu-repo/semantics/bachelorThesis


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