Chronic reparative changes in medium-sized vessels in a case of primary cutaneous anaplastic large-cell lymphoma with angioinvasive features and cytotoxic phenotype: new histopathological findings in line with indolent clinical behavior

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorMacarenco, Ricardo S.
dc.creatorOliveira, Deilson Elgui de
dc.date2015-10-21T13:09:24Z
dc.date2016-10-25T20:59:28Z
dc.date2015-10-21T13:09:24Z
dc.date2016-10-25T20:59:28Z
dc.date2015-05-01
dc.date.accessioned2017-04-06T08:57:49Z
dc.date.available2017-04-06T08:57:49Z
dc.identifierAmerican Journal Of Dermatopathology. Philadelphia: Lippincott Williams &wilkins, v. 37, n. 5, p. 53-56, 2015.
dc.identifier0193-1091
dc.identifierhttp://hdl.handle.net/11449/128378
dc.identifierhttp://acervodigital.unesp.br/handle/11449/128378
dc.identifierhttp://dx.doi.org/10.1097/DAD.0000000000000261
dc.identifierWOS:000353346500001
dc.identifierhttp://journals.lww.com/amjdermatopathology/Abstract/2015/05000/Chronic_Reparative_Changes_in_Medium_Sized_Vessels.17.aspx
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/938934
dc.descriptionAngioinvasion/angiodestruction has been reported in a small subset of primary cutaneous anaplastic large-cell lymphomas (PCALCL). Recently, PCALCL with angioinvasive features and cytotoxic phenotype has been characterized as a variant associated with good clinical outcomes despite worrisome histopathologic features. We report a case of PCALCL with angioinvasive features and cytotoxic phenotype associated with reparative changes on the wall of medium-sized vessels involved by the neoplasm, including intimal fibroblastic proliferation and luminal obliteration. This vascular pattern, although previously unreported in PCALCL, is in accordance with the indolent behavior observed in this entity and provides a further link with lymphomatoid papulosis type E.
dc.languageeng
dc.publisherLippincott Williams &wilkins
dc.relationAmerican Journal Of Dermatopathology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPrimary cutaneous anaplastic large-cell lymphoma
dc.subjectCD30(+) lymphoproliferative disorder
dc.subjectAngiocentric lymphoma
dc.subjectAngioinvasive lymphoma
dc.subjectCutaneous lymphoma
dc.subjectCytotoxic phenotype
dc.subjectEndarteritis obliterans
dc.subjectPseudovasculitis
dc.subjectAngiodestructive
dc.subjectAngioinvasive
dc.subjectMuscular vessels
dc.subjectMedium-sized vessels
dc.titleChronic reparative changes in medium-sized vessels in a case of primary cutaneous anaplastic large-cell lymphoma with angioinvasive features and cytotoxic phenotype: new histopathological findings in line with indolent clinical behavior
dc.typeOtro


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