dc.creator | Payet, Eduardo | |
dc.creator | Perez, Joan | |
dc.creator | Sarria, Gustavo | |
dc.creator | Neciosup, Silvia | |
dc.creator | Berrospi, Francisco | |
dc.creator | Vilchez, Sheila | |
dc.creator | Dunstan, Jorge | |
dc.creator | Perez, Ronald | |
dc.creator | Vassallo, Mauricio | |
dc.creator | Salgado, Santiago | |
dc.creator | Caparachín, Nanto | |
dc.creator | Pinto, Joseph A. | |
dc.creator | Holguin, Alexis | |
dc.date.accessioned | 2022-01-24T14:02:22Z | |
dc.date.accessioned | 2024-05-07T02:39:34Z | |
dc.date.available | 2022-01-24T14:02:22Z | |
dc.date.available | 2024-05-07T02:39:34Z | |
dc.date.created | 2022-01-24T14:02:22Z | |
dc.date.issued | 2021-06-01 | |
dc.identifier | 10.3332/ECANCER.2021.1246 | |
dc.identifier | http://hdl.handle.net/10757/658642 | |
dc.identifier | 17546605 | |
dc.identifier | ecancermedicalscience | |
dc.identifier | 2-s2.0-85109012171 | |
dc.identifier | SCOPUS_ID:85109012171 | |
dc.identifier | 0000 0001 2196 144X | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/9327594 | |
dc.description.abstract | Background: Cancer patients are at higher risk of infection and severity of Coronavirus Disease-19 (COVID-19). Management of patients infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is challenging due to the scarce scientific information and treatment guidelines. In this work, we present our Institutional experience with our first 100 patients with oncological malignancies and COVID-19. Patients and methods: We conducted a cross-sectional study of the first 100 patients hospitalised at the Instituto Nacional de Enfermedades Neoplasicas (Lima, Peru) who were positive for SARS-CoV-2 by reverse transcriptase (RT)-PCR during the period 30 March to 20 June. Clinicopathological variables of the oncological disease as well as risk factors, management and outcomes to COVID-19 were evaluated. Results: The mean age was 43.5 years old (standard deviations: ±24.8) where 57% were male patients. In total, 44%, 37% and 19% were adult patients bearing solid tumours, adults with haematologic malignancies and paediatric patients, respectively. Hypertension was the most frequent comorbidity (23%) followed by chronic lung disease (10%). COVID-19-associated symptoms included cough (65%), fever (57%) and dyspnoea (56%). Twelve percent of patients were asymptomatic. Nosocomial infections were more frequent in paediatric patients (84.2%) than in adult patients (16.0%). Patients with uncontrolled oncological disease were most frequent (72%). Anaemia was present in 67% of patients, 68% had lymphopenia, 62% had ferritin value > 500 mcg/L, 85% had elevated lactate dehydrogenase (LDH), 83% D-dimer > 500 ng/mL and 80% C-Reactive Protein > 8 mg/L. The most common complication was acute respiratory failure (42%). Overall fatality rate was 39% where the main cause of mortality was acute respiratory distress syndrome (64.1%). Conclusion: Paediatric patients had better outcomes than adult populations, and a high number of asymptomatic carriers and nosocomial infection, early diagnosis are recommended. Considering oncological treatments 30 days before COVID-19 diagnosis, our data did not reveal an increased mortality. | |
dc.language | eng | |
dc.publisher | ecancer Global Foundation | |
dc.relation | https://ecancer.org/es/journal/article/1246-characteristics-of-covid-19-in-cancer-patients-a-cross-sectional-study-in-peru/abstract | |
dc.rights | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights | Attribution-NonCommercial-ShareAlike 4.0 International | |
dc.source | Universidad Peruana de Ciencias Aplicadas (UPC) | |
dc.source | Repositorio Academico - UPC | |
dc.source | ecancermedicalscience | |
dc.source | 15 | |
dc.subject | Cancer | |
dc.subject | COVID-19 | |
dc.subject | Mortality | |
dc.subject | SARS-CoV-2 | |
dc.title | Characteristics of COVID-19 in cancer patients: A cross-sectional study in Peru | |
dc.type | info:eu-repo/semantics/article | |