A Randomized Trial of the Topical Effect of Antifibrinolytic Epsilon Aminocaproic Acid on Coronary Artery Bypass Surgery Without Cardiopulmonary Bypass

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorGurian, Danilo Bortolotto
dc.creatorMeneghini, Adriano
dc.creatorAbreu, Luiz Carlos de
dc.creatorMurad, Neif
dc.creatorMatos, Leandro Luongo de
dc.creatorPires, Adilson Casemiro
dc.creatorValenti, Vitor E.
dc.creatorBreda, Joao Roberto
dc.date2015-03-18T15:55:46Z
dc.date2016-10-25T20:35:02Z
dc.date2015-03-18T15:55:46Z
dc.date2016-10-25T20:35:02Z
dc.date2014-09-01
dc.date.accessioned2017-04-06T07:16:08Z
dc.date.available2017-04-06T07:16:08Z
dc.identifierClinical And Applied Thrombosis-hemostasis. Thousand Oaks: Sage Publications Inc, v. 20, n. 6, p. 615-620, 2014.
dc.identifier1076-0296
dc.identifierhttp://hdl.handle.net/11449/117305
dc.identifierhttp://acervodigital.unesp.br/handle/11449/117305
dc.identifier10.1177/1076029613476338
dc.identifierWOS:000342770700009
dc.identifierhttp://dx.doi.org/10.1177/1076029613476338
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/927952
dc.descriptionWe assessed the effect of the topical application of epsilon-aminocaproic antifibrinolytic acid (EACA) on the pericardium of patients submitted to coronary artery bypass graft (CABG) without the use of cardiopulmonary bypass (CPB). This is a prospective, randomized, and double-blind study. We evaluated 26 patients with chronic coronary heart disease indicated for CABG without CPB (EACA and placebo groups). The analysis of the postoperative hematological results showed no difference between groups in hemoglobin and hematocrit. There was no difference between the groups regarding the postoperative bleeding through the drains in the first 24 hours, 48 hours, and accumulated loss until removal of drains. The use of EACA in patients undergoing CABG without CPB presented no difference in the reduction of the amount of bleeding and the need for blood transfusions.
dc.languageeng
dc.publisherSage Publications Inc
dc.relationClinical And Applied Thrombosis-hemostasis
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectbypass
dc.subjectcardiopulmonary
dc.subjectcoronary artery bypass
dc.subjectbypass surgery
dc.subjectcoronary artery
dc.subjectantifibrinolytics
dc.titleA Randomized Trial of the Topical Effect of Antifibrinolytic Epsilon Aminocaproic Acid on Coronary Artery Bypass Surgery Without Cardiopulmonary Bypass
dc.typeOtro


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