Hyaluronic Acid Behavior in the Lamina Propria of the Larynx with Advancing Age

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorBranco, Anete
dc.creatorRodrigues, Sergio Augusto
dc.creatorFabro, Alexandre Todorovic
dc.creatorFonseca-Alves, Carlos Eduardo
dc.creatorGarcia Martins, Regina Helena
dc.date2015-03-18T15:55:46Z
dc.date2016-10-25T20:35:02Z
dc.date2015-03-18T15:55:46Z
dc.date2016-10-25T20:35:02Z
dc.date2014-10-01
dc.date.accessioned2017-04-06T07:16:05Z
dc.date.available2017-04-06T07:16:05Z
dc.identifierOtolaryngology-head And Neck Surgery. London: Sage Publications Ltd, v. 151, n. 4, p. 652-656, 2014.
dc.identifier0194-5998
dc.identifierhttp://hdl.handle.net/11449/117301
dc.identifierhttp://acervodigital.unesp.br/handle/11449/117301
dc.identifier10.1177/0194599814544673
dc.identifierWOS:000342982900020
dc.identifierhttp://dx.doi.org/10.1177/0194599814544673
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/927948
dc.descriptionObjectives. To analyze the hyaluronic acid behavior in the lamina propria of the larynx with advancing age.Study Design. Prospective study.Setting. UNESP-Univ Estadual Paulista, Botucatu Medical School, Brazil.Subjects and Methods. Thirty vocal folds were obtained at necropsy from 10 adult males (30-50 years old) and 20 geriatric males (10: 60-75 years old; 10: over 76 years old). Midmembranous vocal fold sections were subjected to immunohistochemical reactions. Digital imaging software (ImageJ) was used to quantify the hyaluronic acid distribution over the lamina propria of vocal folds, from superficial to deep layers.Results. Hyaluronic acid distribution was homogeneous for the larynges, at both superficial and deep layers (41.6 and 38.5, respectively). For both 30- to 50-year-old men geriatric age groups, hyaluronic acid level was lower at both layers.Conclusion. Hyaluronic acid level in the lamina propria of the larynx of geriatric men decreases with advancing age at both layers of the lamina.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageeng
dc.publisherSage Publications Ltd
dc.relationOtolaryngology-head And Neck Surgery
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectlarynx
dc.subjectlamina propria
dc.subjectvocal folds
dc.subjecthyaluronic acid
dc.subjectpresbyphonia
dc.titleHyaluronic Acid Behavior in the Lamina Propria of the Larynx with Advancing Age
dc.typeOtro


Este ítem pertenece a la siguiente institución