In situ evaluation of low-fluoride toothpastes associated to calcium glycerophosphate on enamel remineralization

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorZaze, A. C. S. F.
dc.creatorDias, A. P.
dc.creatorAmaral, J. G.
dc.creatorMiyasaki, M. L.
dc.creatorSassaki, K. T.
dc.creatorDelbem, Alberto Carlos Botazzo
dc.date2015-03-18T15:53:34Z
dc.date2016-10-25T20:25:10Z
dc.date2015-03-18T15:53:34Z
dc.date2016-10-25T20:25:10Z
dc.date2014-12-01
dc.date.accessioned2017-04-06T07:04:16Z
dc.date.available2017-04-06T07:04:16Z
dc.identifierJournal Of Dentistry. Oxford: Elsevier Sci Ltd, v. 42, n. 12, p. 1621-1625, 2014.
dc.identifier0300-5712
dc.identifierhttp://hdl.handle.net/11449/116594
dc.identifierhttp://acervodigital.unesp.br/handle/11449/116594
dc.identifier10.1016/j.jdent.2014.09.001
dc.identifierWOS:000345512200013
dc.identifier0000-0002-8159-4853
dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2014.09.001
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/927241
dc.descriptionObjectives: This study aimed to evaluate the effect of low-fluoride toothpastes with calcium glycerophosphate (CaGP) on enamel remineralization in situ.Methods: Volunteers (n = 10) wore palatal devices holding four bovine enamel blocks. The treatments involved 5 experimental phases of 3 days each according to the following toothpastes: placebo, 500 ppm F (500 NaF), 500 ppm F with 0.25% CaGP (500 NaF CaGP), 500 ppm F with 0.25% CaGP (500 MFP CaGP) and 1100 ppm F (1100; positive control). After this experimental period, the fluoride, calcium, and phosphorus ion concentrations from enamel were determined. Surface and cross-sectional hardness were also performed. Data were analysed by 1-way ANOVA, Student-Newman-Keuls' test and by Pearson's correlation.Results: The addition of 0.25% CaGP improved the remineralization potential of low-fluoride toothpastes and the NaF as source of fluoride yielded the best results (p < 0.001) as evidenced by the hardness analysis. The 1100 ppm F toothpaste provided higher presence of fluoride in the enamel after remineralization (p < 0.001). The addition of CaGP to the NaF and MFP toothpastes led to similar calcium concentration in the enamel as the observed with the positive control (p = 0.054).Conclusions: Toothpastes with 500 ppm F (NaF or MFP) and CaGP showed similar remineralization potential than 1100 ppm F toothpaste.Clinical significance: Toothpastes containing 500 ppm F associated to CaGP, with both fluoride source (NaF or MFP), showed a potential of remineralization similar to commercial toothpaste. Although there is a need for confirmation in the clinical setting, these results point to an alternative for improving the risk-benefit relationship between fluorosis and dental caries in small children. (C) 2014 Elsevier Ltd. All rights reserved.
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherElsevier B.V.
dc.relationJournal Of Dentistry
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectToothpastes
dc.subjectFluorides
dc.subjectGlycerophosphates
dc.subjectTooth remineralization
dc.subjectDental enamel
dc.titleIn situ evaluation of low-fluoride toothpastes associated to calcium glycerophosphate on enamel remineralization
dc.typeOtro


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