Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorLima Cardoso, Claudia Andrea
dc.creatorCoelho, Roberta Gomes
dc.creatorHonda, Neli Kika
dc.creatorPott, Arnildo
dc.creatorPavan, Fernando Rogério
dc.creatorLeite, Clarice Queico Fujimura
dc.date2014-12-03T13:11:42Z
dc.date2016-10-25T20:14:54Z
dc.date2014-12-03T13:11:42Z
dc.date2016-10-25T20:14:54Z
dc.date2013-10-01
dc.date.accessioned2017-04-06T06:33:33Z
dc.date.available2017-04-06T06:33:33Z
dc.identifierBrazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013.
dc.identifier1984-8250
dc.identifierhttp://hdl.handle.net/11449/113444
dc.identifierhttp://acervodigital.unesp.br/handle/11449/113444
dc.identifierWOS:000333047500017
dc.identifierS1984-82502013000400017.pdf
dc.identifierhttp://dx.doi.org/10.1590/S1984-82502013000400017
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/924186
dc.descriptionSerjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherUniversidade de São Paulo (USP), Conjunto Quimicas
dc.relationBrazilian Journal of Pharmaceutical Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSerjania erecta Radlk/pharmacognosy
dc.subjectSerjania erecta Radlk/ethanolic extract/antioxidant activity
dc.subjectSerjania erecta Radlk/ethanolic extract/antimicrobial activity
dc.subjectSapindaceae/pharmacognosy
dc.subjectCipo-cinco-folhas/pharmacognosy
dc.subjectFlavonoids
dc.subjectMedicinal plants
dc.titlePhenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
dc.typeOtro


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