Gross Motor Deficits in Children Prenatally Exposed to Alcohol: A Meta-analysis

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorLucas, Barbara R.
dc.creatorLatimer, Jane
dc.creatorPinto, Rafael Z.
dc.creatorFerreira, Manuela L.
dc.creatorDoney, Robyn
dc.creatorLau, Mandy
dc.creatorJones, Taryn
dc.creatorDries, Danielle
dc.creatorElliott, Elizabeth J.
dc.date2014-12-03T13:11:40Z
dc.date2016-10-25T20:14:47Z
dc.date2014-12-03T13:11:40Z
dc.date2016-10-25T20:14:47Z
dc.date2014-07-01
dc.date.accessioned2017-04-06T06:33:03Z
dc.date.available2017-04-06T06:33:03Z
dc.identifierPediatrics. Elk Grove Village: Amer Acad Pediatrics, v. 134, n. 1, p. E192-E209, 2014.
dc.identifier0031-4005
dc.identifierhttp://hdl.handle.net/11449/113396
dc.identifierhttp://acervodigital.unesp.br/handle/11449/113396
dc.identifier10.1542/peds.2013-3733
dc.identifierWOS:000338774800024
dc.identifierhttp://dx.doi.org/10.1542/peds.2013-3733
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/924138
dc.descriptionBACKGROUND AND OBJECTIVES: Gross motor (GM) deficits are often reported in children with prenatal alcohol exposure (PAE), but their prevalence and the domains affected are not clear. The objective of this review was to characterize GM impairment in children with a diagnosis of fetal alcohol spectrum disorder (FASD) or moderate to heavy maternal alcohol intake.METHODS: A systematic review with meta-analysis was conducted. Medline, Embase, Allied and Complementary Medicine Database, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, PEDro, and Google Scholar databases were searched. Published observational studies including children aged 0 to <= 18 years with (1) an FASD diagnosis or moderate to heavy PAE, or a mother with confirmed alcohol dependency or binge drinking during pregnancy, and (2) GM outcomes obtained by using a standardized assessment tool. Data were extracted regarding participants, exposure, diagnosis, and outcomes by using a standardized protocol. Methodological quality was evaluated by using Strengthening the Reporting of Observational Studies in Epidemiology guidelines.RESULTS: The search recovered 2881 articles of which 14 met the systematic review inclusion criteria. The subjects' mean age ranged from 3 days to 13 years. Study limitations included failure to report cutoffs for impairment, nonstandardized reporting of PAE, and small sample sizes. The meta-analysis pooled results (n = 10) revealed a significant association between a diagnosis of FASD or moderate to heavy PAE and GM impairment (odds ratio: 2.9; 95% confidence interval: 2.1-4.0). GM deficits were found in balance, coordination, and ball skills. There was insufficient data to determine prevalence.CONCLUSIONS: The significant results suggest evaluation of GM proficiency should be a standard component of multidisciplinary FASD diagnostic services.
dc.languageeng
dc.publisherAmer Acad Pediatrics
dc.relationPediatrics
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectfetal alcohol spectrum disorders
dc.subjectalcohol related neurodevelopmental disorder
dc.subjectalcohol drinking
dc.subjectmotor skills
dc.subjectchild development
dc.titleGross Motor Deficits in Children Prenatally Exposed to Alcohol: A Meta-analysis
dc.typeOtro


Este ítem pertenece a la siguiente institución