Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorAlbas, Avelino
dc.creatorPicolo, Mileia Ricci
dc.creatorSoares, Celio Nereu
dc.creatorUlbano Bachega, Hugo Vagner
dc.creatorTarumoto, Mario Hissamitsu
dc.date2014-12-03T13:11:39Z
dc.date2016-10-25T20:14:44Z
dc.date2014-12-03T13:11:39Z
dc.date2016-10-25T20:14:44Z
dc.date2013-07-30
dc.date.accessioned2017-04-06T06:32:52Z
dc.date.available2017-04-06T06:32:52Z
dc.identifierJournal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 19, 3 p., 2013.
dc.identifier1678-9199
dc.identifierhttp://hdl.handle.net/11449/113379
dc.identifierhttp://acervodigital.unesp.br/handle/11449/113379
dc.identifier10.1186/1678-9199-19-17
dc.identifierWOS:000322840400001
dc.identifierWOS000322840400001.pdf
dc.identifierhttp://dx.doi.org/10.1186/1678-9199-19-17
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/924121
dc.descriptionBackground: Brazil holds annual nationwide public campaigns to vaccinate dogs and cats against rabies. The presence of rabies antibodies in these animals, which are among the main transmitters of rabies to humans, is a good indicator that they are immunized and protected.Methods: In the present study we analyzed 834 serum samples from dogs and cats from the Southeast of Brazil (Presidente Prudente and Dracena cities), 12 months after the 2009 vaccination campaign. We used the technique known as rapid fluorescent focus inhibition test (RFFIT) and considered reactant those sera with values higher 0.5 IU/mL.Results and discussion: Reactant sample results in Presidente Prudente were 153 (51.0%) for dogs and 59 (32.6%) for cats, and in Dracena 110 (52.1%) for dogs and 71 (50.0%) for cats. We discussed vaccine coverage of animals involved in this experiment, and observed low titers < 0.5 IU/mL, especially in cats from Presidente Prudente.Conclusion: According to the results presented in our experiment, we suggest that titers below 0.5 IU/mL are worrisome and that, for multiple reasons, animals should be immunized against rabies in the period between public vaccination campaigns. Hence, the desired vaccine coverage was not accomplished, especially among cats from Presidente Prudente.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageeng
dc.publisherBiomed Central Ltd.
dc.relationJournal of Venomous Animals and Toxins Including Tropical Diseases
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRabies
dc.subjectVaccination
dc.subjectDogs
dc.subjectCats
dc.subjectHumoral immune response
dc.titleHumoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil
dc.typeOtro


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