One-Visit Versus Two-Visit Root Canal Treatment: Effectiveness in the Removal of Endotoxins and Cultivable Bacteria

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorXavier, Ana Claudia C.
dc.creatorMartinho, Frederico C.
dc.creatorChung, Adriana
dc.creatorOliveira, Luciane D.
dc.creatorJorge, Antonio O. C.
dc.creatorValera, Marcia C.
dc.creatorCarvalho, Claudio A. T.
dc.date2014-12-03T13:11:12Z
dc.date2016-10-25T20:13:32Z
dc.date2014-12-03T13:11:12Z
dc.date2016-10-25T20:13:32Z
dc.date2013-08-01
dc.date.accessioned2017-04-06T06:27:52Z
dc.date.available2017-04-06T06:27:52Z
dc.identifierJournal Of Endodontics. New York: Elsevier Science Inc, v. 39, n. 8, p. 959-964, 2013.
dc.identifier0099-2399
dc.identifierhttp://hdl.handle.net/11449/112984
dc.identifierhttp://acervodigital.unesp.br/handle/11449/112984
dc.identifier10.1016/j.joen.2013.04.027
dc.identifierWOS:000323235600001
dc.identifierhttp://dx.doi.org/10.1016/j.joen.2013.04.027
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/923737
dc.descriptionIntroduction: This clinical study was conducted to compare the effectiveness of 1-visit versus 2-visit root canal treatment in removing endotoxins and cultivable bacteria from primarily infected root canals. Methods: Forty-eight primarily infected root canals were selected and randomly divided into 4 groups: G1, 1% NaOCl; G2, 2% chlorhexidine (CHX) gel; 63, 1% NaOCl + Ca(OH)(2); and G4, 2% CHX gel + Ca(OH)(2) (all, n = 12). G1 and G2 involved 1-visit treatment, whereas G3 and 64 involved 2-visit treatment with the placement of Ca(OH)(2) medication for 14 days. Samples were collected before and after root canal procedures. A chromogenic LAL assay test was used to quantify endotoxins. Culture techniques were used to determine bacterial counts. Results: Endotoxins and cultivable bacteria were detected in 100% of the initial samples. All treatment protocols were effective in reducing bacterial load from infected root canals: G1 (1% NaOCl, 99.97%), G2 (2% CHX gel, 99.75%), G3 (1% NaOCl + Ca(OH)(2), 99.90%), and 64 (2% CHX gel + Ca(OH)(2), 96.81%), respectively (P < .05). No differences were found in bacterial load reduction when comparing 1-visit and 2-visit treatment groups, irrespective of the irrigant tested (P > .05). Higher median percentage values of endotoxin reduction were achieved in the 2-visit treatment groups (G3, 98.01% and 64, 96.81%) compared with 1-visit treatment groups (G1, 86.33% and G2, 84.77%) (all P < .05). Conclusions: Both 1-Visit and 2-visit root canal treatment protocols were effective in reducing bacteria and endotoxins, but they were not able to eliminate them in all root canals analyzed. Furthermore, 2-visit root canal treatment protocols were more effective in reducing endotoxins than 1-visit root canal treatment protocols.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherElsevier B.V.
dc.relationJournal of Endodontics
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEndotoxin
dc.subjectLAL
dc.subjectlimulus amebocyte lysate assay
dc.subjectroot canal
dc.titleOne-Visit Versus Two-Visit Root Canal Treatment: Effectiveness in the Removal of Endotoxins and Cultivable Bacteria
dc.typeOtro


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