EFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorGoulart Oliveira-Sequeira, Teresa Cristina
dc.creatorDavid, Erica Boarato
dc.creatorRibeiro, Claudia
dc.creatorGuimaraes, Semiramis
dc.creatorBatista Masseno, Ana Paula
dc.creatorKatagiri, Satie
dc.creatorSequeira, Julio Lopes
dc.date2014-12-03T13:10:57Z
dc.date2016-10-25T20:11:45Z
dc.date2014-12-03T13:10:57Z
dc.date2016-10-25T20:11:45Z
dc.date2014-03-01
dc.date.accessioned2017-04-06T06:24:50Z
dc.date.available2017-04-06T06:24:50Z
dc.identifierRevista Do Instituto De Medicina Tropical De Sao Paulo. Sao Paulo: Inst Medicina Tropical Sao Paulo, v. 56, n. 2, p. 105-109, 2014.
dc.identifier0036-4665
dc.identifierhttp://hdl.handle.net/11449/112677
dc.identifierhttp://acervodigital.unesp.br/handle/11449/112677
dc.identifier10.1590/S0036-46652014000200003
dc.identifierS0036-46652014000200003
dc.identifierWOS:000333031000003
dc.identifierS0036-46652014000200105.pdf
dc.identifierhttp://dx.doi.org/10.1590/S0036-46652014000200003
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/923437
dc.descriptionThe administration of viable Bifidobacterium animalis was tested to induce resistance against Strongyloides venezuelensis infection in mice. Effects on parasite burden, worm length, egg output, and intestinal mucosal histology were evaluated. The oral administration of B. animalis, strain 04450B, starting 14 days before the inoculation of nematode larvae significantly decreased the worm burden and egg output. In probiotic treated animals, the percent reduction of adult worms in the intestine was of 33% and the reduction of egg production was of 21%, compared with those of the control group. The duodenum villous height and villous/crypt ratio were significantly higher in probiotic-treated mice, indicating that this group could be experiencing less intestinal damage. The present findings revealed that the administration of B. animalis for the amelioration of host response to nematode infections is biologically plausible and could have some potential for impacting public health. Meanwhile, further study is needed to delineate the nature and identity of the factor(s) involved in these beneficial effects.
dc.languageeng
dc.publisherInst Medicina Tropical São Paulo
dc.relationRevista do Instituto de Medicina Tropical de São Paulo
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectStrongyloides venezuelensis
dc.subjectBifidobacterium animalis
dc.subjectProbiotics
dc.subjectMice
dc.titleEFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis
dc.typeOtro


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