Osseointegration improvement by plasma electrolytic oxidation of modified titanium alloys surfaces

dc.creatorEcheverry Rendón, Mónica
dc.creatorGalvis Tangarife, Oscar Alonso
dc.creatorQuintero Giraldo, David
dc.creatorPavón Palacio, Juan José
dc.creatorLópez Lacomba, José Luis
dc.creatorJiménez Piqué, Emilio
dc.creatorAnglada, Marc
dc.creatorRobledo Restrepo, Sara María
dc.creatorCastaño González, Juan Guillermo
dc.creatorEcheverría Echeverría, Félix
dc.date2023-06-02T14:18:08Z
dc.date2023-06-02T14:18:08Z
dc.date2015
dc.date.accessioned2024-04-23T18:13:08Z
dc.date.available2024-04-23T18:13:08Z
dc.identifier0957-4530
dc.identifierhttps://hdl.handle.net/10495/35260
dc.identifier10.1007/s10856-015-5408-4.
dc.identifier1573-4838
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9230540
dc.descriptionABSTRACT: Titanium (Ti) is a material frequently used in orthopedic applications, due to its good mechanical properties and high corrosion resistance. However, formation of a non‐adherent fibrous tissue between material and bone drastically could affect the osseointegration process and, therefore, the mechanical stability of the implant. Modifications of topography and configuration of the tissue/ material interface is one of the mechanisms to improve that process by manipulating parameters such as morphology and roughness. There are different techniques that can be used to modify the titanium surface; plasma electrolytic oxidation (PEO) is one of those alternatives, which consists of obtaining porous anodic coatings by controlling parameters such as voltage, current, anodizing solution and time of the reaction. From all of the above factors, and based on previous studies that demonstrated that bone cells sense substrates features to grow new tissue, in this work commercially pure Ti (c.p Ti) and Ti6Al4V alloy samples were modified at their surface by PEO in different anodizing solutions composed of H2SO4 and H3PO4 mixtures. Treated surfaces were characterized and used as platforms to grow osteoblasts; subsequently, cell behavior parameters like adhesion, proliferation and differentiation were also studied. Although the results showed no significant differences in proliferation, differentiation and cell biological activity, overall results showed an important influence of topography of the modified surfaces compared with polished untreated surfaces. Finally, this study offers an alternative protocol to modify surfaces of Ti and their alloys in a controlled and reproducible way in which biocompatibility of the material is not compromised and osseointegration would be improved.
dc.descriptionCOL0007927
dc.descriptionCOL0144399
dc.descriptionCOL0015099
dc.format42
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherSpringer
dc.publisherCentro de Investigación Innovación y Desarrollo de Materiales (CIDEMAT)
dc.publisherGrupo de Biomateriales Avanzados y Medicina Regenerativa (BAMR)
dc.publisherPrograma de Estudio y Control de Enfermedades Tropicales (PECET)
dc.publisherNorwell, Estados Unidos
dc.relationJ. Mater. Sci. Mater. Med.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectAleaciones
dc.subjectAlloys
dc.subjectAdhesión Celular
dc.subjectCell Adhesion
dc.subjectCell Differentiation
dc.subjectDiferenciación Celular
dc.subjectCell Differentiation
dc.subjectLínea Celular
dc.subjectCell Line
dc.subjectMateriales Biocompatibles Revestidos
dc.subjectCoated Materials, Biocompatible
dc.subjectEnsayo de Materiales
dc.subjectMaterials Testing
dc.subjectOseointegración
dc.subjectOsseointegration
dc.subjectOsteoblastos
dc.subjectOsteoblasts
dc.subjectOxidación-Reducción
dc.subjectOxidation-Reduction
dc.subjectTitanio
dc.subjectTitanium
dc.titleOsseointegration improvement by plasma electrolytic oxidation of modified titanium alloys surfaces
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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