dc.creatorVélez Bernal, Iván Darío
dc.creatorYangzom, Thinley
dc.creatorCruz, Israel
dc.creatorBern, Caryn
dc.creatorArgaw, Daniel
dc.creatorDen Boer, Margriet
dc.creatorBhattacharya, Sujit K.
dc.creatorMolina, Ricardo
dc.creatorAlvar, Jorge
dc.date2023-04-11T20:23:36Z
dc.date2023-04-11T20:23:36Z
dc.date2012
dc.date.accessioned2024-04-23T18:08:01Z
dc.date.available2024-04-23T18:08:01Z
dc.identifier0002-9637
dc.identifierhttps://hdl.handle.net/10495/34625
dc.identifier10.4269/ajtmh.2012.12-0211
dc.identifier1476-1645
dc.identifierhttps://doi.org/10.4269/ajtmh.2012.12-0211
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9230435
dc.descriptionABSTRACT: Visceral leishmaniasis was first reported in Bhutan in 2006. We conducted studies of the parasite, possible vectors and reservoirs, and leishmanin skin test and risk factor surveys in three villages. Nineteen cases were reported from seven districts. Parasite typing yielded two novel microsatellite sequences, both related to Indian L. donovani. In one case village, 40 (18.5%) of 216 participants had positive leishmanin skin test results, compared with 3 (4.2%) of 72 in the other case village and 0 of 108 in the control village. Positive results were strongly associated with the village and increasing age. None of the tested dogs were infected. Eighteen sand flies were collected, 13 Phlebotomus species and 5 Sergentomyia species; polymerase chain reaction for leishmanial DNA was negative. This assessment suggests that endemic visceral leishmaniasis transmission has occurred in diverse locations in Bhutan. Surveillance, case investigations, and further parasite, vector, and reservoir studies are needed. The potential protective impact of bed nets should be evaluated.
dc.descriptionCOL0015099
dc.format10
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.publisherPrograma de Estudio y Control de Enfermedades Tropicales (PECET)
dc.publisherBaltimore, Estados Unidos
dc.relationAm. J. Trop. Med. Hyg.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectEndemic Diseases
dc.subjectEnfermedades Endémicas
dc.subjectLeishmaniasis, Visceral
dc.subjectLeishmaniasis Visceral
dc.subjectLeishmania
dc.subjectDisease Transmission, Infectious
dc.subjectTransmisión de Enfermedad Infecciosa
dc.titleEndemic Transmission of Visceral Leishmaniasis in Bhutan
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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