Effect of mercury in the influx and efflux of nutrients in the microalga Desmodesmus armatus

dc.creatorQuevedo Ospina, Catalina
dc.creatorPeñuela Vásquez, Mariana
dc.creatorArroyave Quiceno, Catalina
dc.creatorVillegas Quiceno, Adriana Patricia
dc.date2023-05-03T17:23:10Z
dc.date2023-05-03T17:23:10Z
dc.date2023
dc.date.accessioned2024-04-23T18:05:00Z
dc.date.available2024-04-23T18:05:00Z
dc.identifierQuevedo-Ospina C, Arroyave C, Peñuela-Vásquez M, Villegas A. Effect of mercury in the influx and efflux of nutrients in the microalga Desmodesmus armatus. Aquat Toxicol. 2023 May;258:106496. doi: 10.1016/j.aquatox.2023.106496.
dc.identifier0166-445X
dc.identifierhttps://hdl.handle.net/10495/34813
dc.identifier10.1016/j.aquatox.2023.106496
dc.identifier1879-1514
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9230384
dc.descriptionABSTRACT: Anthropogenic activities such as mining and the metallurgical industry are the main sources of mercury contamination. Mercury is one of the most serious environmental problems in the world. This study aimed to investigate, using experimental kinetic data, the effect of different inorganic mercury (Hg2+) concentrations on the response of microalga Desmodesmus armatus stress. Cell growth, nutrients uptake and mercury ions from the extracellular medium, and oxygen production were determined. A Compartment Structured Model allowed elucidating the phenomena of transmembrane transport, including influx and efflux of nutrients, metal ions and bioadsorption of metal ions on the cell wall, which are difficult to determine experimentally. This model was able to explain two tolerance mechanisms against mercury, the first one was the adsorption of Hg2+ions onto the cell wall and the second was the efflux of mercury ions. The model predicted a competition between internalization and adsorption with a maximum tolerable concentration of 5.29 mg/L of HgCl2. The kinetic data and the model showed that mercury causes physiological changes in the cell, which allow the microalga to adapt to these new conditions to counteract the toxic effects. For this reason, D. armatus can be considered as a Hg-tolerant microalga. This tolerance capacity is associated with the activation of the efflux as a detoxification mechanism that facilitates the maintenance of the osmotic balance for all the modeled chemical species. Furthermore, the accumulation of mercury in the cell membrane suggests the presence of thiol groups associated with its internalization, leading to the conclusion that metabolically active tolerance mechanisms are dominant over passive ones.
dc.descriptionCOL0023715
dc.format15
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.publisherBioprocesos
dc.publisherÁmsterdam, Países Bajos
dc.relationAquat. Toxicol.
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectTransporte Biológico
dc.subjectBiological Transport
dc.subjectIones
dc.subjectIons
dc.subjectMercurio - metabolismo
dc.subjectMercury - metabolism
dc.subjectMicroalgas - metabolismo
dc.subjectMicroalgae - metabolism
dc.subjectContaminantes Químicos del Agua - toxicidad
dc.subjectWater Pollutants, Chemical - toxicity
dc.titleEffect of mercury in the influx and efflux of nutrients in the microalga Desmodesmus armatus
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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