Evaluation of microcrystalline cellulose II (MCCII) as an alternative extrusion-spheronization aid

dc.creatorRojas Camargo, John
dc.creatorKumar, Vijay
dc.date2023-06-09T13:21:54Z
dc.date2023-06-09T13:21:54Z
dc.date2012
dc.date.accessioned2024-04-23T17:59:45Z
dc.date.available2024-04-23T17:59:45Z
dc.identifierRojas J, Kumar V. Evaluation of microcrystalline cellulose II (MCCII) as an alternative extrusion-spheronization aid. Pharmazie. 2012 Jul;67(7):595-7.
dc.identifier0031-7144
dc.identifierhttps://hdl.handle.net/10495/35417
dc.identifier10.1691/ph.2012.1130
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9230217
dc.descriptionABSTRACT: Microcrystalline cellulose II (MCCII) is a different allomorph of MCC that can be used as a filler and a disintegrant for direct compression. MCCII was studied as new pelletization aid with the aim to prepare pellets with a faster drug release than MCCI-based pellets. MCCII-based pellets showed an immediate diphenydramineHCl release profile comparable to that of Benadryl and a faster griseofulvin release than MCCI-based pellets. MCCII offers potential to use as an alternative pelletization aid.
dc.descriptionCOL0003623
dc.format3
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherGovi-Verlag Pharmazautischer Verlag
dc.publisherDiseño y Formulación de Medicamentos Cosméticos y Afines
dc.publisherBerlín, Alemania
dc.relationPharmazie
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCápsulas
dc.subjectCapsules
dc.subjectCelulosa - Química
dc.subjectCellulose - Chemistry
dc.subjectQuímica Farmacéutica
dc.subjectChemistry, Pharmaceutical
dc.subjectDifenhidramina - Química
dc.subjectDiphenhydramine - Chemistry
dc.subjectComposición de Medicamentos
dc.subjectDrug Compounding
dc.subjectExcipientes - Química
dc.subjectExcipients - Chemistry
dc.subjectGriseofulvina - Química
dc.subjectGriseofulvin - Chemistry
dc.subjectCinética
dc.subjectKinetics
dc.subjectMicroesferas
dc.subjectMicrospheres
dc.subjectTamaño de la Partícula
dc.subjectParticle Size
dc.subjectPorosidad
dc.subjectPorosity
dc.subjectProstaglandinas F Sintéticas
dc.subjectProstaglandins F, Synthetic
dc.subjectSolubilidad
dc.subjectSolubility
dc.titleEvaluation of microcrystalline cellulose II (MCCII) as an alternative extrusion-spheronization aid
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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