Nanoformulation prototype based on a natural extract for the potential treatment of type 2 diabetes mellitus

dc.contributor(22 : Tetrahedron Symposium. Catalysis for Sustainable World : 28 de junio al 1 de julio de 2022 : Lisboa, Portugal)
dc.creatorEscobar Chaves, Elkin Leandro
dc.creatorAcín Martínez, Sergio
dc.creatorFernández Culma, Maritza
dc.creatorMuñoz, Diana Lorena
dc.creatorEcheverri, Alexandra
dc.creatorEcheverri López, Luis Fernando
dc.creatorOrozco Holguín, Jahir
dc.creatorBalcázar Morales, Norman
dc.date2023-04-25T16:52:08Z
dc.date2023-04-25T16:52:08Z
dc.date2022-06-28
dc.date.accessioned2024-04-23T17:56:55Z
dc.date.available2024-04-23T17:56:55Z
dc.identifierhttps://hdl.handle.net/10495/34757
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9230138
dc.descriptionABSTRACT: Triterpene-enriched fractions (OBE100) from Eucalyptus tereticornis demonstrated efficiency when administered intraperitoneally to diet-induced obesity (DIO) mouse model to treat obesity-related type 2 diabetes mellitus (T2DM)1; however, its oral administration has not yet led to satisfactory results. We aimed to develop an oral nano formulation that enhanced the promising effect of the OBE 100 fraction, guaranteeing higher stability and bioavailability of the pharmacologically active components present in the natural extract through the oral route.
dc.descriptionCOL0006723
dc.descriptionCOL0015339
dc.descriptionCOL0202529
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherGenética Molecular (GENMOL)
dc.publisherGrupo Tándem Max Planck en Nanobioingeniería
dc.publisherQuímica Orgánica de Productos Naturales
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAtribución-NoComercial-CompartirIgual 2.5 Colombia
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectDiabetes Mellitus Tipo 2
dc.subjectEucalyptus tereticornis
dc.subjectObesidad
dc.subjectObesity
dc.subjectExtractos Vegetales
dc.subjectPlant Extracts
dc.titleNanoformulation prototype based on a natural extract for the potential treatment of type 2 diabetes mellitus
dc.typeinfo:eu-repo/semantics/conferenceObject
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_5794
dc.typehttps://purl.org/redcol/resource_type/EC
dc.typeDocumento de conferencia


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