Nonalcoholic fatty liver disease and metabolic syndrome in postmenopausal women

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorRodrigues, Marcio H.
dc.creatorBruno, Anderson S.
dc.creatorNahas-Neto, Jorge
dc.creatorSantos, Maria Emilia S.
dc.creatorNahás, Eliana Aguiar Petri
dc.date2014-12-03T13:10:33Z
dc.date2016-10-25T20:10:44Z
dc.date2014-12-03T13:10:33Z
dc.date2016-10-25T20:10:44Z
dc.date2014-05-01
dc.date.accessioned2017-04-06T06:20:37Z
dc.date.available2017-04-06T06:20:37Z
dc.identifierGynecological Endocrinology. New York: Informa Healthcare, v. 30, n. 5, p. 325-329, 2014.
dc.identifier0951-3590
dc.identifierhttp://hdl.handle.net/11449/112244
dc.identifierhttp://acervodigital.unesp.br/handle/11449/112244
dc.identifier10.3109/09513590.2013.875992
dc.identifierWOS:000334743400001
dc.identifierhttp://dx.doi.org/10.3109/09513590.2013.875992
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/923010
dc.descriptionNonalcoholic fatty liver disease (NAFLD) is considered the most common cause of chronic liver disease in the Western countries. NAFLD includes a spectrum ranging from a simple steatosis to a nonalcoholic steatohepatitis (NASH) which is defined by the presence of inflammatory infiltrate, cellular necrosis, hepatocyte ballooning, and fibrosis and cirrhosis that can eventually develop into hepatocellular carcinoma. Studies emphasize the role of insulin resistance, oxidative stress, pro-inflammatory cytokines, adipokines in the development and progression of NAFLD. It seems to be independently associated with type II diabetes mellitus, increased triglycerides, decreased HDL-cholesterol, abdominal obesity and insulin resistance. These findings are in accordance with the criteria used in the diagnosis of metabolic syndrome (MetS). Here, we will discuss the current knowledge on the epidemiology, pathophysiology and diagnosis of NAFLD and the association of metabolic syndrome in postmenopausal women.
dc.languageeng
dc.publisherInforma Healthcare
dc.relationGynecological Endocrinology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMenopause
dc.subjectmetabolic syndrome
dc.subjectnonalcoholic fatty liver disease
dc.titleNonalcoholic fatty liver disease and metabolic syndrome in postmenopausal women
dc.typeOtro


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