dc.creatorPerdomo Celis, Federico
dc.creatorTaborda Vanegas, Natalia Andrea
dc.creatorRugeles López, María Teresa
dc.date2023-03-14T22:35:43Z
dc.date2023-03-14T22:35:43Z
dc.date2017
dc.date.accessioned2024-04-23T17:52:00Z
dc.date.available2024-04-23T17:52:00Z
dc.identifierhttps://hdl.handle.net/10495/34010
dc.identifier10.3389/fimmu.2017.01241
dc.identifier1664-3224
dc.identifierhttps://www.frontiersin.org/articles/10.3389/fimmu.2017.01241/full
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9229988
dc.descriptionABSTRACT: The lymphoid follicle is critical for the development of humoral immune responses. Cell circulation to this site is highly regulated by the differential expression of chemokine receptors. This feature contributes to the establishment of viral reservoirs in lymphoid follicles and the development of some types of malignancies that are able to evade immune surveillance, especially conventional CD8+ T cells. Interestingly, a subtype of CD8+ T cells located within the lymphoid follicle (follicular CD8+ T cells) was recently described; these cells have been proposed to play an important role in viral and tumor control, as well as to modulate humoral and T follicular helper cell responses. In this review, we summarize the knowledge on this novel CD8+ T cell population, its origin, function, and potential role in health and disease, in particular, in the context of the infection by the human immunodeficiency virus.
dc.descriptionCOL0012444
dc.format13
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Research Foundation
dc.publisherInmunovirología
dc.publisherLausana, Suiza
dc.relationFront. Immunol.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectLinfocitos T
dc.subjectT-Lymphocytes
dc.subjectLinfocitos B
dc.subjectB-Lymphocytes
dc.subjectT-Lymphocytes, Cytotoxic
dc.subjectLinfocitos T Citotóxicos
dc.subjectCD8 Antigens
dc.subjectAntígenos CD8
dc.subjectReceptors, CXCR5
dc.subjectReceptores CXCR5
dc.titleFollicular CD8 + T Cells : Origin, Fuction and Importance During HIV Infection
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_dcae04bc
dc.typehttps://purl.org/redcol/resource_type/ARTREV
dc.typeArtículo de revisión


Este ítem pertenece a la siguiente institución