Resistencia de Plasmodium falciparum A Tres Fármacos Antimaláricos En Turbo (Antioquia, Colombia), 1998
Resistance of Plasmodium falciparum to three antimalarials in Turbo (Antioquia, Colombia), 1998
dc.creator | Blair Trujillo, Silvia | |
dc.creator | Lacharme Lora, Leidy | |
dc.creator | Carmona Fonseca, Jaime | |
dc.creator | Tobón Castaño, Alberto | |
dc.date | 2023-06-09T17:12:08Z | |
dc.date | 2023-06-09T17:12:08Z | |
dc.date | 2001 | |
dc.date.accessioned | 2024-04-23T17:47:48Z | |
dc.date.available | 2024-04-23T17:47:48Z | |
dc.identifier | Blair, Silvia,Lacharme, Leidy L,Carmona Fonseca, Jaime,Tobón, Alberto (2001) Resistencia de plasmodium falciparum a tres fármacos antimaláricos en Turbo: Antioquia, Colombia,1998. Rev Panam Salud Publica;9(1) -,jan. 2001. Retrieved from http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892001000100006&lng=pt&nrm=iso | |
dc.identifier | 1020-4989 | |
dc.identifier | https://hdl.handle.net/10495/35439 | |
dc.identifier | 1680 5348 | |
dc.identifier | https://iris.paho.org/handle/10665.2/8758 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/9229919 | |
dc.description | RESUMEN: En 1998, se determinó in vivo e in vitro la frecuencia y el grado de resistencia de Plasmodium falciparum a los tres fármacos antimaláricos (cloroquina, amodiaquina y sulfadoxina/ pirimetamina) más utilizados en el municipio de Turbo (zona de Urabá, Antioquia, Colombia) en una muestra representativa de la población con malaria. Se realizaron análisis clínicos y parasitológicos durante 14 días según la prueba estándar recomendada por la Organización Mundial de la Salud. In vivo, P. falciparum mostró resistencia a la cloroquina, amodiaquina y sulfadoxina/pirimetamina con una frecuencia de 97, 7 y 13%, respectivamente; in vitro, las cifras correspondientes fueron de 21, 23 y 9%, respectivamente. La concordancia entre los resultados in vivo e in vitro fue de 23% para la cloroquina | |
dc.description | ABSTRACT: In 1998 we determined in vivo and in vitro the frequency and the degree of resistance of Plasmodium falciparum to the three antimalarials (chloroquine, amodiaquine, and sulfadoxine/pyrimethamine) most utilized in the municipality of Turbo (in the area of Urabá, Antioquia, Colombia), in a sample representative of the population with malaria. We carried out clinical and parasitological analyses over a 14-day period using the standard test recommended by the World Health Organization. In vivo, P. falciparum showed resistance to chloroquine, amodiaquine, and sulfadoxine/ pyrimethamine, with a frequency of 97%, 7%, and 13%, respectively. In vitro, the corresponding figures were 21%, 23%, and 9%, respectively. For chloroquine the level of agreement between the in vivo and in vitro results was 23%. | |
dc.description | COL0007524 | |
dc.description | COL0047449 | |
dc.format | 7 | |
dc.format | application/pdf | |
dc.format | application/pdf | |
dc.language | spa | |
dc.publisher | Organización Panamericana de la Salud | |
dc.publisher | Grupo Malaria | |
dc.publisher | Salud y Comunidad | |
dc.publisher | Washington, Estados Unidos | |
dc.relation | Rev. Panam. Salud Pública. | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
dc.rights | http://purl.org/coar/access_right/c_abf2 | |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | Malaria | |
dc.subject | Vacunas contra la Malaria | |
dc.subject | Malaria Vaccines | |
dc.subject | Enfermedades Endémicas | |
dc.subject | Endemic Diseases | |
dc.subject | Farmacorresistencia Microbiana | |
dc.subject | Drug Resistance, Microbial | |
dc.subject | Malaria - Colombia | |
dc.subject | Comprimidos | |
dc.subject | Tablets | |
dc.title | Resistencia de Plasmodium falciparum A Tres Fármacos Antimaláricos En Turbo (Antioquia, Colombia), 1998 | |
dc.title | Resistance of Plasmodium falciparum to three antimalarials in Turbo (Antioquia, Colombia), 1998 | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.type | http://purl.org/coar/resource_type/c_2df8fbb1 | |
dc.type | https://purl.org/redcol/resource_type/ART | |
dc.type | Artículo de investigación |