Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorVieira, Narciso Almeida
dc.creatorBorgo, Hilton Coimbra
dc.creatorDalben, Gisele da Silva
dc.creatorBachega, Maria Irene
dc.creatorMarques Pereira, Paulo Camara
dc.date2014-12-03T13:10:31Z
dc.date2016-10-25T20:10:41Z
dc.date2014-12-03T13:10:31Z
dc.date2016-10-25T20:10:41Z
dc.date2013-07-01
dc.date.accessioned2017-04-06T06:20:21Z
dc.date.available2017-04-06T06:20:21Z
dc.identifierBrazilian Journal of Microbiology. São Paulo: Soc Brasileira Microbiologia, v. 44, n. 3, p. 835-838, 2013.
dc.identifier1517-8382
dc.identifierhttp://hdl.handle.net/11449/112219
dc.identifierhttp://acervodigital.unesp.br/handle/11449/112219
dc.identifierWOS:000332062100026
dc.identifierS1517-83822013000300026.pdf
dc.identifierhttp://dx.doi.org/10.1590/S1517-83822013000300026
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/922985
dc.descriptionThis study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair.
dc.languageeng
dc.publisherSoc Brasileira Microbiologia
dc.relationBrazilian Journal of Microbiology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcleft palate
dc.subjectcleft palate/surgery
dc.subjectenvironmental microbiology
dc.subjectfeces
dc.subjectsurgery/plastic
dc.titleEvaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
dc.typeOtro


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