dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSchmit, Juliano
dc.creatorMiot, Hélio Amante
dc.date2014-12-03T13:10:31Z
dc.date2016-10-25T20:10:39Z
dc.date2014-12-03T13:10:31Z
dc.date2016-10-25T20:10:39Z
dc.date2014-03-01
dc.date.accessioned2017-04-06T06:20:14Z
dc.date.available2017-04-06T06:20:14Z
dc.identifierRevista Da Associacao Medica Brasileira. Sao Paulo: Assoc Medica Brasileira, v. 60, n. 2, p. 131-138, 2014.
dc.identifier0104-4230
dc.identifierhttp://hdl.handle.net/11449/112205
dc.identifierhttp://acervodigital.unesp.br/handle/11449/112205
dc.identifier10.1590/1806-9282.60.02.010
dc.identifierS0104-42302014000200131
dc.identifierWOS:000336012800008
dc.identifierS0104-42302014000200131.pdf
dc.identifierhttp://dx.doi.org/10.1590/1806-9282.60.02.010
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/922971
dc.descriptionObjective: To investigate the influence of a regular oral use of acetylsalicylic acid in the prevalence of actinic keratosis.Methods: A case-control study with dermatologic outpatients above 50 years of age assessed between 2009 and 2011. Cases were defined as those who had been under regular use of oral acetylsalicylic acid for more than six consecutive months. The assessment focused on: age, sex, skin-type, tobacco smoking, use of medication, occurrence of individual or family skin cancer, and sunscreen and sun exposure habits. Actinic keratoses were counted in the medial region of the face and upper limbs. Counts were adjusted by co-variables based on a generalized linear model.Results: A total of 74 cases and 216 controls were assessed. The median time of acetylsalicylic acid use was 36 months. Cases differed from controls as to the highest age, highest prevalence of use of angiotensin-converting enzyme inhibitors and fewer keratosis on the face and on the upper limbs (p < 0.05). The multivariate model showed that the use of acetylsalicylic acid was associated to lower counts of face actinic keratosis and upper-limb erythematous actinic keratosis (p < 0.05), regardless of other risk factors.Conclusion: The regular use of oral acetylsalicylic acid for more than six months was associated to a lower prevalence of actinic keratosis, especially facial and erythematous ones.
dc.languageeng
dc.publisherAssociação Médica Brasileira
dc.relationRevista da Associação Médica Brasileira
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectactinic keratosis
dc.subjectacetylsalicylic acid
dc.subjectprevalence
dc.subjectrisk factors
dc.titleOral acetylsalicylic acid and prevalence of actinic keratosis
dc.typeOtro


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