Epigenetic disorders and altered gene expression after use of Assisted Reproductive Technologies in domestic cattle

dc.creatorUrrego Álvarez, Rodrigo Antonio
dc.creatorRodríguez Osorio, Nélida
dc.creatorNiemann, Heiner
dc.date2023-04-13T19:13:13Z
dc.date2023-04-13T19:13:13Z
dc.date2014
dc.date.accessioned2024-04-23T13:57:02Z
dc.date.available2024-04-23T13:57:02Z
dc.identifierUrrego R, Rodriguez-Osorio N, Niemann H. Epigenetic disorders and altered gene expression after use of Assisted Reproductive Technologies in domestic cattle. Epigenetics. 2014 Jun;9(6):803-15. doi: 10.4161/epi.28711.
dc.identifier1559-2294
dc.identifierhttps://hdl.handle.net/10495/34670
dc.identifier10.4161/epi.28711
dc.identifier1559-2308
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9228766
dc.descriptionABSTRACT: The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an important tool for improving the production of dairy and beef cattle. A frequently employed ART in the cattle industry is in vitro production of embryos. However, bovine in vitro produced embryos differ greatly from their in vivo produced counterparts in many facets, including developmental competence. The lower developmental capacity of these embryos could be due to the stress to which the gametes and/or embryos are exposed during in vitro embryo production, specifically ovarian hormonal stimulation, follicular aspiration, oocyte in vitro maturation in hormone supplemented medium, sperm handling, gamete cryopreservation, and culture of embryos. The negative effects of some ARTs on embryo development could, at least partially, be explained by disruption of the physiological epigenetic profile of the gametes and/or embryos. Here, we review the current literature with regard to the putative link between ARTs used in bovine reproduction and epigenetic disorders and changes in the expression profile of embryonic genes. Information on the relationship between reproductive biotechnologies and epigenetic disorders and aberrant gene expression in bovine embryos is limited and novel approaches are needed to explore ways in which ARTs can be improved to avoid epigenetic disorders.
dc.descriptionCOL0001262
dc.format13
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherEpigenetics Society
dc.publisherTaylor & Francis
dc.publisherCENTAURO
dc.publisherPhiladelphia, Estados Unidos
dc.relationEpigenetics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEnfermedades de los Bovinos - genética
dc.subjectCattle Diseases - genetics
dc.subjectBovinos
dc.subjectCattle
dc.subjectTécnicas de Cultivo de Embriones
dc.subjectEmbryo Culture Techniques
dc.subjectDesarrollo Embrionario - genética
dc.subjectEmbryonic Development - genetics
dc.subjectEpigénesis Genética
dc.subjectEpigenesis, Genetic
dc.subjectExpresión Génica
dc.subjectGene Expression
dc.subjectTécnicas de Transferencia Nuclear
dc.subjectNuclear Transfer Techniques
dc.subjectOocitos - trasplante
dc.subjectOocytes - transplantation
dc.subjectTécnicas Reproductivas Asistidas
dc.subjectReproductive Techniques, Assisted
dc.subjectManejo de Especímenes - veterinaria
dc.subjectSpecimen Handling - veterinary
dc.subjectEspermatozoides - trasplante
dc.subjectSpermatozoa - transplantation
dc.subjectSuperovulación - genética
dc.subjectSuperovulation - genetics
dc.subjectTécnicas de Maduración In Vitro de los Oocitos
dc.subjectIn Vitro Oocyte Maturation Techniques
dc.subjectMetilación de ADN
dc.subjectDNA Methylation
dc.titleEpigenetic disorders and altered gene expression after use of Assisted Reproductive Technologies in domestic cattle
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_dcae04bc
dc.typehttps://purl.org/redcol/resource_type/ARTREV
dc.typeArtículo de revisión


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