Neuropsychiatric symptoms in the prodromal stages of dementia

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorStella, Florindo
dc.creatorRadanovic, Marcia
dc.creatorBalthazar, Marcio L. F.
dc.creatorCanineu, Paulo R.
dc.creatorSouza, Leonardo C. de
dc.creatorForlenza, Orestes V.
dc.date2014-12-03T13:07:08Z
dc.date2016-10-25T19:58:49Z
dc.date2014-12-03T13:07:08Z
dc.date2016-10-25T19:58:49Z
dc.date2014-05-01
dc.date.accessioned2017-04-06T06:03:12Z
dc.date.available2017-04-06T06:03:12Z
dc.identifierCurrent Opinion In Psychiatry. Philadelphia: Lippincott Williams & Wilkins, v. 27, n. 3, p. 230-235, 2014.
dc.identifier0951-7367
dc.identifierhttp://hdl.handle.net/11449/111278
dc.identifierhttp://acervodigital.unesp.br/handle/11449/111278
dc.identifier10.1097/YCO.0000000000000050
dc.identifierWOS:000335349500011
dc.identifierhttp://dx.doi.org/10.1097/YCO.0000000000000050
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/922058
dc.descriptionPurpose of reviewTo critically discuss the neuropsychiatric symptoms in the prodromal stages of dementia in order to improve the early clinical diagnosis of cognitive and functional deterioration.Recent findingsCurrent criteria for cognitive syndrome, including Alzheimer's disease, comprise the neuropsychiatric symptoms in addition to cognitive and functional decline. Although there is growing evidence that neuropsychiatric symptoms may precede the prodromal stages of dementia, these manifestations have received less attention than traditional clinical hallmarks such as cognitive and functional deterioration. Depression, anxiety, apathy, irritability, agitation, sleep disorders, among other symptoms, have been hypothesized to represent a prodromal stage of dementia or, at least, they increase the risk for conversion from minor neurocognitive disorder to major neurocognitive disorder. Longitudinal investigations have provided increased evidence of progression to dementia in individuals with minor neurocognitive disorder when neuropsychiatric symptoms also were present.SummaryAlthough neuropsychiatric symptoms are strongly associated with a higher risk of cognitive and functional deterioration, frequently the clinician does not acknowledge these conditions as increasing the risk of dementia. When the clinician accurately diagnoses neuropsychiatric symptoms in the prodromal stage of dementia, he could early establish appropriate treatment and, may be, delay the beginning of clinical and functional deterioration.
dc.languageeng
dc.publisherLippincott Williams & Wilkins
dc.relationCurrent Opinion In Psychiatry
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAlzheimer's disease
dc.subjectmild behavior impairment
dc.subjectminor neurocognitive disorder
dc.subjectneuropsychiatric symptoms
dc.subjectprodromal dementia
dc.titleNeuropsychiatric symptoms in the prodromal stages of dementia
dc.typeOtro


Este ítem pertenece a la siguiente institución