Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSoares, Luciana Arantes
dc.creatorSardi, Janaína De Cássia Orlandi
dc.creatorGullo, Fernanda Patrícia
dc.creatorPitangui, Nayla De Souza
dc.creatorScorzoni, Liliana
dc.creatorLeite, Fernanda Sangalli
dc.creatorMendes-Giannini, Maria José Soares
dc.creatorAlmeida, Ana Marisa Fusco
dc.date2014-10-01T13:08:55Z
dc.date2016-10-25T19:46:05Z
dc.date2014-10-01T13:08:55Z
dc.date2016-10-25T19:46:05Z
dc.date2013-12-01
dc.date.accessioned2017-04-06T05:55:22Z
dc.date.available2017-04-06T05:55:22Z
dc.identifierBrazilian Journal of Microbiology. Sociedade Brasileira de Microbiologia, v. 44, n. 4, p. 1035-1041, 2013.
dc.identifier1517-8382
dc.identifierhttp://hdl.handle.net/11449/110220
dc.identifierhttp://acervodigital.unesp.br/handle/11449/110220
dc.identifier10.1590/S1517-83822014005000011
dc.identifierS1517-83822013000400003
dc.identifierWOS:000333959600003
dc.identifierS1517-83822013000400003.pdf
dc.identifier0000-0002-8059-0826
dc.identifierhttp://dx.doi.org/10.1590/S1517-83822014005000011
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/921022
dc.descriptionMillions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
dc.languageeng
dc.publisherSociedade Brasileira de Microbiologia
dc.relationBrazilian Journal of Microbiology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectdermatophytes
dc.subjectfilamentous fungi
dc.subjectnatural products
dc.subjectsynthetic product
dc.titleAnti dermatophytic therapy: prospects for the discovery of new drugs from natural products
dc.typeOtro


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