Effect of temperature in bursting of thalamic reticular cells
Efecto de la temperature en las descargas en ráfaga de la células del núcleo reticular del tálamo
| dc.creator | Hernandez Bustos, Oscar Emilio | |
| dc.creator | E. Zurek, Eduardo | |
| dc.creator | Vera Mellao, David | |
| dc.creator | Cepeda Emiliani, Alfonso | |
| dc.date | 2018-11-21T13:14:55Z | |
| dc.date | 2018-11-21T13:14:55Z | |
| dc.date | 2018 | |
| dc.date.accessioned | 2023-10-03T19:41:28Z | |
| dc.date.available | 2023-10-03T19:41:28Z | |
| dc.identifier | 0120-5552 | |
| dc.identifier | http://hdl.handle.net/11323/1610 | |
| dc.identifier | Corporación Universidad de la Costa | |
| dc.identifier | REDICUC - Repositorio CUC | |
| dc.identifier | https://repositorio.cuc.edu.co/ | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/9171462 | |
| dc.description | Objective: To show the relation between the four parameters associated to bursting discharges of the thalamic reticular cells (TRNn): the maximum firing frequency (fmax) and the temperature at which it occurs (Tfmax), the range of temperatures defined as the full width at half maximum (∆Th ) and the maximum specific low threshold calcium conductance (GT). Materials and Methods: In order to simulate the TRNn bursting activity, a computational simulation model was implemented using the NEURON software, which incorporates morphological and electrophysiological data, and stimuli properties closely related to reality. Results: It was found that there are nonlinear relations between the parameters. The fmax frequency follows a quadratic growth with temperature and tends asymptotically towards a limit value with the maximum calcium conductance. In the same manner, ∆Th increases until reaching a limit value as function of fmax and GT . However, the increment per frequency unit is bigger than the increment per conductance unit. Conclusions: Four equations were obtained that model the relations between the parameters associated to bursting discharges of the TRNn in rats and other neurons with similar characteristics in different animal species. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Salud Uninorte | |
| dc.rights | Atribución – No comercial – Compartir igual | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.subject | TRN neuron | |
| dc.subject | Computational simulation | |
| dc.subject | Firing frequency | |
| dc.subject | Temperature | |
| dc.subject | Burst firing | |
| dc.title | Effect of temperature in bursting of thalamic reticular cells | |
| dc.title | Efecto de la temperature en las descargas en ráfaga de la células del núcleo reticular del tálamo | |
| dc.type | Artículo de revista | |
| dc.type | http://purl.org/coar/resource_type/c_6501 | |
| dc.type | Text | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | http://purl.org/redcol/resource_type/ART | |
| dc.type | info:eu-repo/semantics/acceptedVersion | |
| dc.type | http://purl.org/coar/version/c_ab4af688f83e57aa |