Effects of the consumption of polyunsaturated fatty acids on the oxidative status of adult dogs

dc.creatorE. Pacheco, Gabriel F.
dc.creatorC. Bortolin, Rafael
dc.creatorR. Chaves, Paloma
dc.creatorF. Moreira, José C.
dc.creatorM. Kessler, Alexandre
dc.creatorTrevizan, Luciano
dc.date2019-04-11T22:45:42Z
dc.date2019-04-11T22:45:42Z
dc.date2018-07-30
dc.date.accessioned2023-10-03T19:32:12Z
dc.date.available2023-10-03T19:32:12Z
dc.identifier0021-8812
dc.identifierhttp://hdl.handle.net/11323/3026
dc.identifierCorporación Universidad de la Costa
dc.identifierREDICUC - Repositorio CUC
dc.identifierhttps://repositorio.cuc.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9170505
dc.descriptionThe present study evaluated the alterations of the oxidative stress markers in adult dogs fed with high levels of PUFA from the mixture of soybean oil enriched with docosahexaenoic acid (DHA) and supplemented with a natural algae-based antioxidant (AOX). Twelve healthy adult (2 years old) Beagle dogs (6 males and 6 females, 11.20 ± 1.92 kg BW), were distributed in 2 completely randomized blocks design and fed with 4 experimental diets coated with 2 lipid sources: saturated (13% bovine tallow) or unsaturated (13% soybean oil enriched with DHA), supplemented or not with 500 mg of AOX for 4 wk, intercalated with a 4 wk adaptation period. Blood samples were collected on days 0, 15, and 30 of each block. Glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), sulfhydryl group (SH), protein carbonylation, thiobarbituric acid reactive substances (TBARS), and total reactive antioxidant potential (TRAP) were evaluated in the serum, while GSH-Px, SOD, glutathione S-transferase (GST), catalase (CAT), SH, and TBARS were measured in erythrocytes. There was no significant difference in most of the oxidative markers evaluated. In contrast, GST activity in erythrocytes was greater in the animals that consumed the diets coated with bovine tallow compared to dogs that consumed diets coated with soybean oil enriched with DHA (P < 0.05). Serum from dogs fed on diets supplemented with AOX presented greater TRAP values (P < 0.05). These data demonstrate that the concentrations of unsaturated fatty acids used in the diets for dogs were not sufficient to cause large changes in the oxidative status. It was not possible to evaluate the efficiency of the natural antioxidant in maintaining the oxidative balance of the animals as it appears that the oxidative status of the dogs was not challenged by the unsaturated diets. Our findings also suggest that dogs, as descendants from carrion carnivores, may have some natural protection against oxidation
dc.formatapplication/pdf
dc.languageeng
dc.publisherJournal of Animal Science
dc.relationhttps://academic.oup.com/jas/article-abstract/96/11/4590/5061274
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dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Estados Unidos de América
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/us/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subjectalgal meal
dc.subjectcanines
dc.subjectfree radicals
dc.subjectlipid oxidation
dc.subjectoxidative stress
dc.titleEffects of the consumption of polyunsaturated fatty acids on the oxidative status of adult dogs
dc.typePre-Publicación
dc.typehttp://purl.org/coar/resource_type/c_816b
dc.typeText
dc.typeinfo:eu-repo/semantics/preprint
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/redcol/resource_type/ARTOTR
dc.typeinfo:eu-repo/semantics/acceptedVersion
dc.typehttp://purl.org/coar/version/c_ab4af688f83e57aa


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