dc.creatorGaitan Quintero, Gustavo
dc.creatorCamargo, Loida
dc.creatorLópez Velásquez, Norman Darío
dc.creatorGonzález, Miguel
dc.date2021-11-23T19:19:39Z
dc.date2021-11-23T19:19:39Z
dc.date2021
dc.date.accessioned2023-10-03T19:19:58Z
dc.date.available2023-10-03T19:19:58Z
dc.identifier2090-6668
dc.identifier2090-6676
dc.identifierhttps://hdl.handle.net/11323/8899
dc.identifierhttps://doi.org/10.1155/2021/6646115
dc.identifierCorporación Universidad de la Costa
dc.identifierREDICUC - Repositorio CUC
dc.identifierhttps://repositorio.cuc.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9169644
dc.descriptionIntroduction. Melkersson–Rosenthal syndrome (MRS) is a neuromucocutaneous disorder characterized by the following classic symptom triad: peripheral facial paralysis, orofacial edema, and scrotal or fissured tongue. It is rare, and since most of the patients are oligo- or monosymptomatic, it makes it difficult to diagnose. Clinical Case. We present a 26-year-old male patient with a history of sickle cell trait, untreated snoring, and left peripheral facial paralysis when he was 11 years old. +is was an overall 20- day clinical profile that started with left peripheral facial paralysis, which was accompanied by moderate-intensity occipital pulsatile headaches. Additionally, the patient experienced paresthesias in the tongue and feelings of labial edema. After one week, he manifested peripheral facial paralysis on the right side. Physical examination revealed bilateral peripheral facial paralysis, mild labial edema, and a scrotal or fissured tongue. +e patient received corticosteroids, which resulted in improvement of the edema and facial paralysis. Discussion. MRS is a rare disorder that predominantly affects women, typically starting in their 20s or 30s. +e etiology is unknown. However, a multifactorial origin that involves environmental factors and a genetic predisposition has been proposed, which causes a dysfunction of the local immune system and autonomic nervous system (ANS) and an appearance of granulomatous inflammation in the lips and tongue. Facial paralysis usually appears later on; however, it can occur from its clinical debut. +ere are no curative treatments. +erapy is focused on modulating the patient’s immune response, and relapses are frequent.
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languagespa
dc.publisherCorporación Universidad de la Costa
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dc.rightsCC0 1.0 Universal
dc.rightshttp://creativecommons.org/publicdomain/zero/1.0/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.sourceCase Reports in Neurological Medicine
dc.sourcehttps://www.hindawi.com/journals/crinm/2021/6646115/
dc.subjectFacial paralysis
dc.subjectMelkersson–Rosenthal
dc.subjectSyndrome
dc.titlePresentation of bilateral facial paralysis in Melkersson–Rosenthal syndrome
dc.typeArtículo de revista
dc.typehttp://purl.org/coar/resource_type/c_6501
dc.typeText
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/redcol/resource_type/ART
dc.typeinfo:eu-repo/semantics/acceptedVersion
dc.typehttp://purl.org/coar/version/c_ab4af688f83e57aa


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