Carga de COVID-19 en Córdoba, un departamento de Colombia: resultados de los años de vida ajustados por discapacidad

dc.creatorLozano, Ana
dc.creatorSalcedo Mejía, Fernando
dc.creatorZakzuk, Josefina
dc.creatorALVIS ZAKZUK, NELSON RAFAEL
dc.creatorMoyano-Tamara, Lina
dc.creatorSerrano-Coll, Héctor
dc.creatorGastelbondo, Bertha Irina
dc.creatorMattar, Salim
dc.creatorALVIS-ZAKZUK, NELSON J.
dc.creatorAlvis-Guzmán, Nelson
dc.date2023-09-22T14:26:29Z
dc.date2024
dc.date2023-09-22T14:26:29Z
dc.date2023
dc.date.accessioned2023-10-03T19:19:12Z
dc.date.available2023-10-03T19:19:12Z
dc.identifierAna Lozano, Fernando Salcedo-Mejía, Josefina Zakzuk, Nelson Rafael Alvis-Zakzuk, Lina Moyano-Tamara, Héctor Serrano-Coll, Bertha Gastelbondo, Salim Mattar, Nelson J. Alvis-Zakzuk, Nelson Alvis-Guzman, Burden of COVID-19 in Córdoba, A Department of Colombia: Results of Disability-Adjusted Life-Years: Carga de COVID-19 en Córdoba, un Departamento de Colombia: Resultados de los Años de Vida Ajustados por Discapacidad, Value in Health Regional Issues, Volume 37, 2023, Pages 9-17, ISSN 2212-1099, https://doi.org/10.1016/j.vhri.2023.03.005.
dc.identifier2212-1099
dc.identifierhttps://hdl.handle.net/11323/10509
dc.identifier10.1016/j.vhri.2023.03.005
dc.identifier2212-1102
dc.identifierCorporación Universidad de la Costa
dc.identifierREDICUC - Repositorio CUC
dc.identifierhttps://repositorio.cuc.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9169517
dc.descriptionObjectives: This study aimed to estimate the burden of acute COVID-19 in Córdoba, one of the most affected departments (states) in Colombia, through the estimation of disability-adjusted life-years (DALYs). Methods: DALYs were estimated based on the number of cases of severe acute respiratory syndrome coronavirus 2 infection cases reported by official Colombian sources. A transition probability matrix among severity states was calculated using data obtained from a retrospective cohort that included 1736 COVID-19 confirmed subjects living in Córdoba. Results: Córdoba had 120.23 deaths per 100 000 habitants during the study period (March 2020 to April 2021). Estimated total DALYs were 49 243 (2692 DALYs per 100 000 inhabitants), mostly attributed to fatal cases (99.7%). On average, 25 years of life were lost because of death by this infection. A relevant proportion of years of life lost because of COVID-19 (46.6%) was attributable to people , 60 years old and was greater in men. People $ 60 years old showed greater risk of progression to critical state than people between the age of 35 and 60 years (hazard ratio 2.5; 95% confidence interval 2.5-12.5) and younger than 35 years (9.1; 95% confidence interval 4.0-20.6). Conclusion: In Córdoba, premature mortality because of COVID-19 was substantially represented by people , 60 years old and was greater in males. Our data may be representative of Latin American populations with great infection spread during the first year of the pandemic and contribute to novel methodological aspects and parameter estimations that may be useful to measure COVID-19 burden in other countries of the region.
dc.descriptionObjetivos: Estimar la carga de COVID-19 aguda en Córdoba, uno de los departamentos (estados) más afectados de Colombia, a través de la estimación de años de vida ajustados por discapacidad (AVISAS). Métodos: Los AVISAS se estimaron con base en el número de casos de infección por severe acute respiratory syndrome coronavirus 2 reportados por fuentes oficiales colombianas. Se calculó una matriz de probabilidad de transición entre estados de gravedad a partir de los datos obtenidos de una cohorte retrospectiva que incluyó a 1.736 sujetos confirmados con COVID19 residentes en Córdoba. Resultados: Córdoba tuvo 120,23 defunciones por cada 100.000 habitantes durante el periodo de estudio (marzo de 2020 a abril de 2021). Los AVISAS totales estimados fueron 49.243 (2.692 AV por 100.000 habitantes), en su mayoría atribuidos a los casos mortales (99,7%). En promedio, se perdieron 25 años de vida debido a las muertes secundarias a esta infección. Una proporción relevante de años de vida perdidos a causa de la COVID-19 (46,6%) fue atribuible a las personas menores de 60 años y fue mayor en los hombres. Las personas $ 60 años presentaron un mayor riesgo de progresión a estado crítico en comparación con las personas entre 35-60 años (hazard ratio 2,5; intervalo de confianza 95% 2,5-12,5) y menores de 35 años (9,1; intervalo de confianza 95% 4,0-20,6). Conclusión: En Córdoba, la mortalidad prematura por COVID-19 estuvo sustancialmente representada por las personas menores de 60 años y fue mayor en el sexo masculino. Nuestros datos pueden ser representativos de poblaciones latinoamericanas con gran propagación de infecciones durante el primer año de la pandemia y aportan aspectos metodológicos novedosos para la estimación de parámetros que pueden ser útiles para medir la carga de COVID-19 en otros países de la región.
dc.format9 páginas
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier USA
dc.publisherUnited States
dc.relationValue in Health Regional Issues
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dc.rightsr ª 2023 International Society for Health Economics and Outcomes Research. Published by Elsevier Inc.
dc.rightsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.rightshttp://purl.org/coar/access_right/c_f1cf
dc.sourcehttps://www.sciencedirect.com/science/article/pii/S221210992300033X
dc.subjectCoronavirus infections
dc.subjectDisability-adjusted life-year
dc.subjectSevere acute respiratory syndrome
dc.subjectYears of life lost
dc.subjectYears lived with disability
dc.subjectAños de vida perdidos
dc.subjectInfecciones por coronavirus
dc.subjectAños vividos con discapacidad
dc.subjectAños de vida ajustados por discapacidad
dc.titleBurden of COVID-19 in córdoba, a department of Colombia: results of disability-adjusted life-years
dc.titleCarga de COVID-19 en Córdoba, un departamento de Colombia: resultados de los años de vida ajustados por discapacidad
dc.typeArtículo de revista
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typeText
dc.typeinfo:eu-repo/semantics/article
dc.typehttp://purl.org/redcol/resource_type/ART
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/version/c_970fb48d4fbd8a85
dc.coverageColombia
dc.coverageCórdoba


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