Endocannabinoids and heart rate variability alterations after exposure to prolonged intensive physical exercise of the hellenic navy seals

dc.creatorMourtakos, Stamatis
dc.creatorVassiliou, Georgia
dc.creatorKontoangelos, Konstantinos
dc.creatorPhilippou, Anastassios
dc.creatorTzavellas, Elias
dc.creatorTornero Aguilera, José Francisco
dc.creatorClemente-Suárez, Vicente Javier
dc.creatorPapageorgiou, Charalabos
dc.creatorSidossis, Labros S.
dc.creatorPapageorgiou, Christos
dc.date2022-06-21T15:38:08Z
dc.date2022-06-21T15:38:08Z
dc.date2021-12-21
dc.date.accessioned2023-10-03T19:12:06Z
dc.date.available2023-10-03T19:12:06Z
dc.identifier1661-7827
dc.identifierhttps://hdl.handle.net/11323/9274
dc.identifierhttps://doi.org/10.3390/ijerph19010028
dc.identifier10.3390/ijerph19010028
dc.identifier1660-4601
dc.identifierCorporación Universidad de la Costa
dc.identifierREDICUC - Repositorio CUC
dc.identifierhttps://repositorio.cuc.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9168821
dc.descriptionBackground: Recent research indicates that both endocannabinoids (eCB) and heart rate variability (HRV) are associated with stress-induced experiences. However, these underlying mech-anisms are not elucidated. The present study aims to investigate whether exposure to acute and chronic stress conditions can give rise to measurable changes, both to the peripheral eCB ligands and HRV. Methods: Thirteen candidates under intense preparation for their enlistment in the Hellenic Navy SEALs (HNS) participated in the study. All subjects underwent mental state examination, while HRV variables in time and frequency domain recordings were acquired. Furthermore, at baseline and 30 days after prolonged and intensive physical exercise, hair was collected to measure eCB ligands, such as anandamide (AEA), 2-arachidonoylglycerol (2-AG), and the N-acyl ethanolamine (NAE) molecules: palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). Results: Comparing basal hair concentrations of eCB ligands before and after intense physical exercise, we found that AEA, PEA, and OEA were notably increased, whereas no differences were observed regarding the ligand 2-AG. Furthermore, there were observed associations between the concentrations of peripheral eCB ligands, both at baseline and after the prolonged physical exercise and the time and frequency domains of HRV. Conclusions: These findings suggest that endocannabinoid–HRV interrelations might share a short-term, and long-term adaptability of the changes in self-regulation associated with stress. Further studies will be required to determine the validity of peripheral eCB signaling and HRV as a biomarker for different aspects of the stress response. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
dc.format10 páginas
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media S.A.
dc.publisherSwitzerland
dc.relationInternational Journal of Environmental Research and Public Health
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dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
dc.rightsAtribución 4.0 Internacional (CC BY 4.0)
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.sourcehttps://www.mdpi.com/1660-4601/19/1/28
dc.subjectEndocannabinoids
dc.subjectHeart rate variability
dc.subjectAcute stress
dc.subjectPhysical exercise
dc.subjectSpecial forces
dc.titleEndocannabinoids and heart rate variability alterations after exposure to prolonged intensive physical exercise of the hellenic navy seals
dc.typeArtículo de revista
dc.typehttp://purl.org/coar/resource_type/c_6501
dc.typeText
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/redcol/resource_type/ART
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/version/c_ab4af688f83e57aa


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