Pathological effects of ECHINOSTOMA PARAENSEI infection associated with pyogenic abscesses caused by PSEUDOMONAS AERUGINOSA in swiss mice

dc.creatorSilva Garcia, Juberlan
dc.creatorSimões, Raquel de Oliveira
dc.creatorMota, Ester
dc.creatorSoares dos Santos, Incerlande
dc.creatorMaldonado Júnior, Arnaldo
dc.date2021-02-22
dc.date.accessioned2023-09-29T11:49:33Z
dc.date.available2023-09-29T11:49:33Z
dc.identifierhttps://revistas.ufg.br/iptsp/article/view/66670
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9095895
dc.descriptionThe trematode Echinostoma paraensei is an intestinal parasite transmitted by ingestion of the infectious stage of metacercariae. For scientific purposes, its life cycle has been maintained in the laboratory, allowing analysis using various biological approaches. Different parasite isolates have revealed atypical patterns of migration and establishment in ectopic sites in Swiss-Webster mice. During the investigation of the biological life cycle of an E. paraensei isolate from the silvatic rodent Nectomys squamipes collected in the municipality of Rio Bonito (State of Rio de Janeiro), a bacterial coinfection with Pseudomonas aeruginosa was observed, which produced anatomopathological alterations, mainly in the liver, bile ducts, pancreas, and small intestine. The main macroscopic signs were the whitish suppurative pyogenic punctual lesions. The histological sections stained by hematoxylin-eosin showed an intense inflammatory reaction formed by mononuclear cells and macrophages surrounding the bile ducts, although the hepatic parenchyma still presented its normal aspect. Thus, pyogenic abscesses can be associated with E. paraensei infection depending on the strain and aggravating pathogenesis in the definitive host.KEY WORDS: Liver abscess; Swiss mice; trematode infection.en-US
dc.descriptionThe trematode Echinostoma paraensei is an intestinal parasite transmitted by ingestion of the infectious stage of metacercariae. For scientific purposes, its life cycle has been maintained in the laboratory, allowing analysis using various biological approaches. Different parasite isolates have revealed atypical patterns of migration and establishment in ectopic sites in Swiss-Webster mice. During the investigation of the biological life cycle of an E. paraensei isolate from the silvatic rodent Nectomys squamipes collected in the municipality of Rio Bonito (State of Rio de Janeiro), a bacterial coinfection with Pseudomonas aeruginosa was observed, which produced anatomopathological alterations, mainly in the liver, bile ducts, pancreas, and small intestine. The main macroscopic signs were the whitish suppurative pyogenic punctual lesions. The histological sections stained by hematoxylin-eosin showed an intense inflammatory reaction formed by mononuclear cells and macrophages surrounding the bile ducts, although the hepatic parenchyma still presented its normal aspect. Thus, pyogenic abscesses can be associated with E. paraensei infection depending on the strain and aggravating pathogenesis in the definitive host.KEY WORDS: Liver abscess; Swiss mice; trematode infection.pt-BR
dc.formatapplication/pdf
dc.languageeng
dc.publisherUniversidade Federal de Goiáspt-BR
dc.relationhttps://revistas.ufg.br/iptsp/article/view/66670/36500
dc.rightsCopyright (c) 2021 Revista de Patologia Tropical / Journal of Tropical Pathologypt-BR
dc.sourceRevista de Patologia Tropical / Journal of Tropical Pathology; Vol. 50 No. 1 (2021); 40-48en-US
dc.sourceRevista de Patologia Tropical / Journal of Tropical Pathology; v. 50 n. 1 (2021); 40-48pt-BR
dc.source1980-8178
dc.source0301-0406
dc.titlePathological effects of ECHINOSTOMA PARAENSEI infection associated with pyogenic abscesses caused by PSEUDOMONAS AERUGINOSA in swiss miceen-US
dc.titlePathological effects of ECHINOSTOMA PARAENSEI infection associated with pyogenic abscesses caused by PSEUDOMONAS AERUGINOSA in swiss micept-BR
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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