TONGUE FUNCTION, SALIVARY FLOW RATE AND IgA, IgM AND IgG TOTAL SALIVARY LEVELS IN CHRONIC CHAGASIC PATIENTS

dc.creatorCristina Martins, Gabrielle
dc.creatorBeghini, Marcela
dc.creatorBarbosa, Ana Rita Campos
dc.creatorNogueira, Ruchele Dias
dc.creatorRodrigues, Bárbara Rocha
dc.creatorPereira, Thiago Lima
dc.creatorde Faria, Juliana Barbosa
dc.creatorRodrigues, Denise Bertulucci Rocha
dc.creatorde Lima Pereira, Sanivia Aparecida
dc.date2019-08-20
dc.date.accessioned2023-09-29T11:49:28Z
dc.date.available2023-09-29T11:49:28Z
dc.identifierhttps://revistas.ufg.br/iptsp/article/view/58434
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9095857
dc.descriptionAlthough microscopic alterations have been detected in tongues and salivary glands of chagasic patients and the identification of biomarkers in saliva has proved advantageous, there are no studies evaluating tongue function and total salivary IgA, IgG and IgM levels in chronic chagasic patients. The aim of this study was to evaluate tongue function, salivary flow rate, and total salivary IgA, IgG and IgM levels comparing chronic and non-chronic chagasic individuals. 37 patients were selected: chronic cardiac chagasic patients (n=6), chronic chagasic patients with the associated form of the disease (cardiopathy and megaesophagus) (n=11), and nonchagasic individuals (n=20). The tongue function underwent a phonoaudiological evaluation.The salivary f low rate was measured by sialometry. The total salivary IgA, IgG and IgM levels were evaluated by sandwich ELISA assay. Chagasic patients with the associated form of the disease presented higher salivary flow rate and lower salivary protein levels. No significant differences were noted in the lingual function or in the total salivary immunoglobulin levels among the groups. Although patients with chagasic megaesophagus presented higher levels of salivary flow and lower salivary protein, the fact that there were no significant differencesin lingual function and total salivary immunoglobulin levels among the groups led to the conclusion that chronic chagas disease does not modify the lingual function or the total IgA, IgG and IgM salivary levels. The present study was the first to evaluate the function of the tongue and salivary total immunoglobulin levels in Chagas disease. en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherUniversidade Federal de Goiáspt-BR
dc.relationhttps://revistas.ufg.br/iptsp/article/view/58434/34351
dc.rightsCopyright (c) 2019 Revista de Patologia Tropical / Journal of Tropical Pathologypt-BR
dc.sourceRevista de Patologia Tropical / Journal of Tropical Pathology; Vol. 48 No. 2 (2019); 109-120en-US
dc.sourceRevista de Patologia Tropical / Journal of Tropical Pathology; v. 48 n. 2 (2019); 109-120pt-BR
dc.source1980-8178
dc.source0301-0406
dc.titleTONGUE FUNCTION, SALIVARY FLOW RATE AND IgA, IgM AND IgG TOTAL SALIVARY LEVELS IN CHRONIC CHAGASIC PATIENTSen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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