Candidate genes for male and female reproductive traits in Canchim beef cattle

dc.creatorBuzanskas, Marcos Eli
dc.creatorGrossi, Daniela do Amaral
dc.creatorVentura, Ricardo Vieira
dc.creatorSchenkel, Flavio Schramm
dc.creatorChud, Tatiane Cristina Seleguim
dc.creatorStafuzza, Nedenia Bonvino
dc.creatorRola, Luciana Diniz
dc.creatorMeirelles, Sarah Laguna Conceição
dc.creatorMokry, Fabiana Barichello
dc.creatorMudadu, Maurício de Alvarenga
dc.creatorHiga, Roberto Hiroshi
dc.creatorSilva, Marcos Vinícius Gualberto Barbosa da
dc.creatorAlencar, Maurício Mello de
dc.creatorRegitano, Luciana Correia de Almeida
dc.creatorAlmeida, Luciana Correia de
dc.creatorMunar, Danísio Prado
dc.date2019-09-06T11:55:23Z
dc.date2019-09-06T11:55:23Z
dc.date2017
dc.date.accessioned2023-09-28T20:09:08Z
dc.date.available2023-09-28T20:09:08Z
dc.identifierBUZANKAS, M. E. Candidate genes for male and female reproductive traits in Canchim beef cattle. Journal of Animal Science and Biotechnology, [S. l.], n. 8, p. 1-10, 2017. DOI: https://doi.org/10.1186/s40104-017-0199-8.
dc.identifierhttp://repositorio.ufla.br/jspui/handle/1/36693
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9045711
dc.descriptionBackground Beef cattle breeding programs in Brazil have placed greater emphasis on the genomic study of reproductive traits of males and females due to their economic importance. In this study, genome-wide associations were assessed for scrotal circumference at 210 d of age, scrotal circumference at 420 d of age, age at first calving, and age at second calving, in Canchim beef cattle. Data quality control was conducted resulting in 672,778 SNPs and 392 animals. Results Associated SNPs were observed for scrotal circumference at 420 d of age (435 SNPs), followed by scrotal circumference at 210 d of age (12 SNPs), age at first calving (six SNPs), and age at second calving (four SNPs). We investigated whether significant SNPs were within genic or surrounding regions. Biological processes of genes were associated with immune system, multicellular organismal process, response to stimulus, apoptotic process, cellular component organization or biogenesis, biological adhesion, and reproduction. Conclusions Few associations were observed for scrotal circumference at 210 d of age, age at first calving, and age at second calving, reinforcing their polygenic inheritance and the complexity of understanding the genetic architecture of reproductive traits. Finding many associations for scrotal circumference at 420 d of age in various regions of the Canchim genome also reveals the difficulty of targeting specific candidate genes that could act on fertility; nonetheless, the high linkage disequilibrium between loci herein estimated could aid to overcome this issue. Therefore, all relevant information about genomic regions influencing reproductive traits may contribute to target candidate genes for further investigation of causal mutations and aid in future genomic studies in Canchim cattle to improve the breeding program.
dc.formatapplication/pdf
dc.languageen_US
dc.publisherSpringer Nature
dc.rightsAttribution 4.0 International
dc.rightsacesso aberto
dc.rightshttp://creativecommons.org/licenses/by/4.0/
dc.sourceJournal of Animal Science and Biotechnology
dc.subjectCattle - Animal breeding
dc.subjectCattle - Composite breed
dc.subjectGenome-wide association
dc.subjectGenomic data
dc.subjectSingle nucleotide
dc.subjectBovinos - Criação
dc.subjectGado - Raça composta
dc.subjectAssociação em todo o genoma
dc.subjectDados genômicos
dc.subjectNucleotídeo único
dc.titleCandidate genes for male and female reproductive traits in Canchim beef cattle
dc.typeArtigo


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