dc.creatorMatos, Leandro Faria de
dc.creatorPereira, Stela Márcia
dc.creatorKaminagakura, Estela
dc.creatorMarques, Leandro Silva
dc.creatorPereira, Cássio Vicente
dc.creatorvan der Bilt, Andries
dc.creatorPereira, Luciano José
dc.date2020-02-07T11:57:12Z
dc.date2020-02-07T11:57:12Z
dc.date2010-02
dc.date.accessioned2023-09-28T20:03:36Z
dc.date.available2023-09-28T20:03:36Z
dc.identifierMATOS, L. F. de et al. Relationships of beta-blockers and anxiolytics intake and salivary secretion, masticatory performance and taste perception. Archives of Oral Biology, [S.l.], v. 55, n. 2, p. 164-169, Feb. 2010.
dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0003996909003021
dc.identifierhttp://repositorio.ufla.br/jspui/handle/1/38953
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9043431
dc.descriptionObjective Assess the influence of salivary flow on physiological parameters of the stomatognathic system in patients who take beta-blockers or anxiolytic medications. Design Sixty patients were divided into three groups based on the following criteria: Group 1, control (n = 20; no use of medication); Group 2, use of antihypertensive beta-blockers (n = 20); and Group 3, use of benzodiazepine anxiolytics (n = 20). Salivary flow was assessed by determining stimulated and non-stimulated flow/minute. The quantification of the sense of taste was determined on a visual analogue scale (VAS) using solutions of 0.9% NaCl (salty), 50% sucrose (sweet), 20% unsweetened coffee (bitter) and 4.2% vinegar (sour). The DMFT index (number of decayed/missing/filled teeth) was determined by a calibrated examination, following the criteria of the World Health Organization (WHO). Masticatory performance was assessed with an Optosil comminution test and Rosim–Ramler equation. Results The results did not reveal a significant correlation between salivary flow and masticatory performance (p > 0.05). We observed significant decreased non-stimulated salivary flow for Group 2 (p = 0.05) when compared to controls. However, taste perception was not influenced by salivary secretion amongst groups. Furthermore, we observed a significant negative correlation between non-stimulated salivary flow and DMFT in Group 1 (p = 0.02; r = −0.52). Conclusions Patients under beta-blockers therapy presented reduced non-stimulated salivary flow when compared to controls, without influencing the sense of taste or masticatory performance. The use of anxiolytics did not affect salivary flow and taste perception in the studied sample.
dc.languageen_US
dc.publisherElsevier
dc.rightsrestrictAccess
dc.sourceArchives of Oral Biology
dc.subjectMastication
dc.subjectAnxiolytic
dc.subjectAntihypertensive
dc.subjectTaste
dc.titleRelationships of beta-blockers and anxiolytics intake and salivary secretion, masticatory performance and taste perception
dc.typeArtigo


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