Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase

dc.creatorAngelis-Pereira, Michel Cardoso de
dc.creatorBarcelos, Maria de Fátima Píccolo
dc.creatorPereira, Juciane de Abreu Ribeiro
dc.creatorPereira, Rafaela Corrêa
dc.creatorSouza, Raimundo Vicente de
dc.date2018-11-09T11:25:47Z
dc.date2018-11-09T11:25:47Z
dc.date2017
dc.date.accessioned2023-09-28T20:00:19Z
dc.date.available2023-09-28T20:00:19Z
dc.identifierANGELIS-PEREIRA, M. C. de et al. Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase. Acta Cirurgica Brasileira, São Paulo, v. 32, n. 12, p. 1013-1025, 2017.
dc.identifierhttp://repositorio.ufla.br/jspui/handle/1/31685
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9042137
dc.descriptionPurpose: To investigate the fatty acid content of different fat sources and evaluate the effect of them on plasma and hepatic lipids and on the fatty acid profile of the brain tissue of Wistar rats. Methods: Thirty male albino Wistar rats received for 59 days, the following diets: diet added of margarine with low content of polyunsaturated fatty acids (PUFA); diet added of margarine with high content of PUFA; diet added of butter; diet added of hydrogenated vegetable fat; diet added of soybean oil. Fatty acid profile of the lipid sources, blood and hepatic lipids fractions and fatty acid profile of the brain tissue were determined. Results: Margarine consumption of provided different responses as to concentrations of blood and hepatic lipid fractions. Intake of butter and hydrogenated increased LDL-c/HDL-c ratio, being the steepest increase promoted by hydrogenated vegetable fat, which also raised LDL-c levels expressively. All fats used in the treatments reduced the cerebral concentration of docosahexaenoic acid when compared to soybean oil (control). Conclusion: The different fat sources commonly consumed by population provided different responses in vivo. This is particularly relevant considering the role of these lipids in the incidence and prevention of cardiovascular diseases.
dc.formatapplication/pdf
dc.languageen_US
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.rightsAttribution 4.0 International
dc.rightsacesso aberto
dc.rightshttp://creativecommons.org/licenses/by/4.0/
dc.sourceActa Cirurgica Brasileira
dc.subjectDyslipidemias
dc.subjectLipid metabolism
dc.subjectRats
dc.titleEffect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase
dc.typeArtigo


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