dc.creatorSILVA, DANIEL J. da
dc.creatorDURAN, ADRIANA
dc.creatorFONSECA, FERNANDO L.A.
dc.creatorPARRA, DUCLERC F.
dc.creatorBUENO, RODRIGO F.
dc.creatorROSA, DERVAL S.
dc.date2023
dc.date2023-06-29T14:08:52Z
dc.date2023-06-29T14:08:52Z
dc.date.accessioned2023-09-28T14:26:12Z
dc.date.available2023-09-28T14:26:12Z
dc.identifier0169-4332
dc.identifierhttp://repositorio.ipen.br/handle/123456789/34105
dc.identifier623
dc.identifier10.1016/j.apsusc.2023.157015
dc.identifier0000-0002-6481-0155
dc.identifier83.7
dc.identifier93
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9004313
dc.descriptionSurface modification corresponds to a set of viable technological approaches to introduce antimicrobial properties in materials that do not have such characteristics. Antimicrobial materials are important to prevent the proliferation of microorganisms and minimize the transmission of diseases caused by pathogens. Herein, poly (lactic acid) (PLA) was decorated with nanocones through copper sputtering followed by a plasma etching. Antiviral assays by Quantitative Reverse Transcription-Polymerase Chain Reaction (RT-qPCR) show that nanostructured Cu-coated PLA has high antiviral activity against Omicron SARS-CoV-2, showing a relative reduction in the amplified RNA (78.8 ?? 3.9 %). Atomic Force Microscopy (AFM), X-ray Photoelectron Spectroscopy (XPS), and wear-resistance tests show that 20 wear cycles disrupt the surface nanocone patterns and significantly reduce the Cu content at the surface of the nanostructured Cu-coated PLA, leading to total loss of the antiviral properties of nanostructured PLA against Omicron SARS-CoV-2.
dc.descriptionConselho Nacional de Desenvolvimento Cient??fico e Tecnol??gico (CNPq)
dc.descriptionCoordena????o de Aperfei??oamento de Pessoal de N??vel Superior (CAPES)
dc.descriptionCNPq: 305819/2017???8; 402432/2020???7
dc.descriptionCAPES: 88881.504639/2020???01
dc.format1-9
dc.relationApplied Surface Science
dc.rightsopenAccess
dc.subjectcoronaviruses
dc.subjectpolymers
dc.subjectlactic acid
dc.subjectcopper
dc.subjectplasma
dc.subjectnanotechnology
dc.subjectwear
dc.titleOmicron SARS-CoV-2 antiviral on poly(lactic acid) with nanostructured copper coating
dc.typeArtigo de peri??dico
dc.coverageI


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