| dc.description | Introduction: Prostate cancer is the second most common cancer in men worldwide. In Brazil, regional disparities in incidences of
intermediate and high-risk in late-diagnosed PC cases are expected. Objective: To investigate the clinical and demographic profiles of patients
treated with metastatic castration-resistant prostate cancer (mCRPC) in Brazil, using real-world data from public databases. Method:
Prostate cancer data from the Brazilian cancer registries were filtered from Brazilian public databases from 2008 to 2018. The number
of health institutions and registries at a cancer public database were used to separate the Brazilian Federative Units into two comparison
groups. mCRPC patients were estimated by using a combination of filters of staging and treatment (Tx, Nx and M1 + chemotherapy).
The patients??? median age and the number and type of treatments were evaluated. Results: A total of 325,987 patients with prostate cancer
and 5,367 patients with mCRPC were identified. The median age of the mCRPC patients was 63 years. The percentage of patients who
underwent one, two or three treatments was 21.0%, 43.2% and 28.1%, respectively. In addition, management differences were noticed
depending on the group analyzed. Conclusion: The results revealed regional discrepancies in the distribution of registered mCRPC
patients in the Brazilian territory and in their treatment. This information can be used to strengthen the recently updated treatment and
improve the palliative care offered. This work presents suggestions to improve specific prostate cancer databases. | |
