dc.creatorOLIVEIRA, LUCAS N. de
dc.creatorNASCIMENTO, ERIBERTO O. do
dc.creatorCALDAS, LINDA V.E.
dc.date2021
dc.date2021-12-09T18:16:18Z
dc.date2021-12-09T18:16:18Z
dc.date.accessioned2023-09-28T14:19:50Z
dc.date.available2023-09-28T14:19:50Z
dc.identifier1474-905X
dc.identifierhttp://repositorio.ipen.br/handle/123456789/32377
dc.identifier11
dc.identifier20
dc.identifier10.1007/s43630-021-00088-w
dc.identifier0000-0002-7362-2455
dc.identifier59.78
dc.identifier85.00
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9002597
dc.descriptionPhotodynamic therapy has been recently studied, bringing innovations regarding the reduction of exposure time to light by the patient. This work aimed to investigate the feasibility of using Coutarea hexandra (Jacq.) K. Schum (CHS) as a detector in photodynamic therapy measurements. For this, an irradiator containing a blue LED bulb lamp was utilized. The CHS samples were irradiated with ten doses from 0.60 up to 6.0 kJ/cm2, and six concentrations were prepared (1, 2, 3, 4, 5, and 6 mg/ml) for the CHS detector samples. After irradiation, the detector samples were evaluated using UV???Vis spectrophotometry. The results showed the behavior of the CHS detector with doses and concentrations, its sensitivity, and its linearity was also evaluated both by Wavelength Method (WM) and the Kernel Principal Component Regression (KPCR) Statistical Method. The values obtained indicate that this method can be applied to the CHS sample detector. In conclusion, the CHS is a promising detector in the field of photodynamic therapy.
dc.descriptionConselho Nacional de Desenvolvimento Cient??fico e Tecnol??gico (CNPq)
dc.descriptionFunda????o de Amparo ?? Pesquisa do Estado de S??o Paulo (FAPESP)
dc.descriptionCNPq: 104486/2019-8; 164981/2020-9; 301335/2016-8
dc.descriptionFAPESP: 18/05982-0
dc.format1381-1395
dc.relationPhotochemical and Photobiological Sciences
dc.rightsopenAccess
dc.subjectphotodynamic therapy
dc.subjectlight emitting diodes
dc.subjectultraviolet radiation
dc.subjectlight bulbs
dc.subjectradiation detectors
dc.titleA new natural detector for irradiations with blue LED light source in photodynamic therapy measurements via UV???Vis spectroscopy
dc.typeArtigo de peri??dico
dc.coverageI


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