Evaluation of biokinetics and dosimetry in [131I]-NaI therapies

dc.creatorLIMA, B.L.
dc.creatorALMEIDA, J.S.
dc.creatorPOTIENS, M.P.A.
dc.creatorPELISSONI, R.A.
dc.creatorSAPIENZA, M.T.
dc.creatorBUCHPIGUEL, C.A.
dc.creatorWILLEGAIGNON, J.
dc.date2020
dc.date2020-10-22T15:30:17Z
dc.date2020-10-22T15:30:17Z
dc.date.accessioned2023-09-28T14:16:30Z
dc.date.available2023-09-28T14:16:30Z
dc.identifier2319-0612
dc.identifierhttp://repositorio.ipen.br/handle/123456789/31474
dc.identifier1A
dc.identifier8
dc.identifier10.15392/bjrs.v8i1A.1082
dc.identifier0000-0002-4049-6720
dc.identifierSem Percentil
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9001697
dc.descriptionThis study evaluate the possibility of restricting the current image quantification (ROI) from the whole body to a small area in thigh for therapy planning. Whole body planar images were obtained from 13 patients after the administration of 131I tracer dose, and OLINDA/EXM software was used for internal dose calculation. The average value of half-life time was 16.46 ?? 3.45 h in whole body quantification, compared to 14.07 ?? 2.89 h in thigh. The average absorbed dose in bone marrow from the whole body quantification was 0.0519 ?? 0.0250 mGy/MBq, whilst the absorbed dose provided by the thigh quantification represented 87% of this value, with up to 95% in time reduction for dose calculation. Such doses become similar when a correction factor of 1.13 is applied in thigh dose results (p=0.67), which is within the variation coefficient assumed to internal dosimetry (20%). This study shows the possibility of a significant time reduction in internal dose calculation applied to therapy planning.
dc.format1-13
dc.relationBrazilian Journal of Radiation Sciences
dc.rightsopenAccess
dc.sourceInternational Joint Conference Radio, September 16-20, 2019, S??o Paulo, SP
dc.subjectabsorbed radiation doses
dc.subjectbone marrow
dc.subjectdosimetry
dc.subjectiodine 131
dc.subjectlimbs
dc.subjectneoplasms
dc.subjectpatients
dc.subjectplanning
dc.subjectradionuclide kinetics
dc.subjectsingle photon emission computed tomography
dc.subjectthyroid
dc.subjectwhole-body irradiation
dc.titleEvaluation of biokinetics and dosimetry in [131I]-NaI therapies
dc.typeArtigo de peri??dico
dc.coverageN


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