Aedes aegypti midgut remodeling during metamorphosis

dc.creatorFernande, Kenner Morais
dc.creatorNeves, Clóvis Andrade
dc.creatorSerrão, José Eduardo
dc.creatorMartins, Gustavo Ferreira
dc.date2018-04-04T10:51:46Z
dc.date2018-04-04T10:51:46Z
dc.date2014-01-26
dc.date.accessioned2023-09-27T22:16:35Z
dc.date.available2023-09-27T22:16:35Z
dc.identifier13835769
dc.identifierhttps://doi.org/10.1016/j.parint.2014.01.004
dc.identifierhttp://www.locus.ufv.br/handle/123456789/18632
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8973020
dc.descriptionThe Aedes aegypti midgut is restructured during metamorphosis; its epithelium is renewed by replacing the digestive and endocrine cells through stem or regenerative cell differentiation. Shortly after pupation (white pupae) begins, the larval digestive cells are histolized and show signs of degeneration, such as autophagic vacuoles and disintegrating microvilli. Simultaneously, differentiating cells derived from larval stem cells form an electron-dense layer that is visible 24 h after pupation begins. Forty-eight hours after pupation onset, the differentiating cells yield an electron-lucent cytoplasm rich in microvilli and organelles. Dividing stem cells were observed in the fourth instar larvae and during the first 24 h of pupation, which suggests that stem cells proliferate at the end of the larval period and during pupation. This study discusses various aspects of the changes during midgut remodeling for pupating A. aegypti.
dc.formatpdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherParasitology International
dc.relationv. 63, Issue 3, p. 506-512, June 2014
dc.rightsElsevier Ireland Ltd. All rights reserved.
dc.subjectMidgut
dc.subjectDevelopment
dc.subjectAedes aegypti
dc.subjectEndocrine cells
dc.subjectStem cells
dc.subjectRegenerative cells
dc.titleAedes aegypti midgut remodeling during metamorphosis
dc.typeArtigo


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