Brasil | Artigo
dc.creatorVerardo, Lucas L.
dc.creatorLopes, Marcos S.
dc.creatorMathur, Pramod
dc.creatorMadsen, Ole
dc.creatorSilva1, Fabyano F.
dc.creatorGroenen, Martien A. M.
dc.creatorKnol, Egbert F.
dc.creatorLopes, Paulo S.
dc.creatorGuimarães, Simone E. F.
dc.date2018-05-21T10:29:51Z
dc.date2018-05-21T10:29:51Z
dc.date2017-06-02
dc.date.accessioned2023-09-27T22:13:16Z
dc.date.available2023-09-27T22:13:16Z
dc.identifier1432-1777
dc.identifierhttp://dx.doi.org/10.1007/s00335-017-9696-5
dc.identifierhttp://www.locus.ufv.br/handle/123456789/19734
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8972299
dc.descriptionFor reproductive traits such as total number born (TNB), variance due to different environments is highly relevant in animal breeding. In this study, we aimed to perform a gene-network analysis for TNB in pigs across different environments using genomic reaction norm models. Thus, based on relevant single-nucleotide polymorphisms and linkage disequilibrium blocks across environments obtained from GWAS, different sets of candidate genes having biological roles linked to TNB were identified. Network analysis across environment levels resulted in gene interactions consistent with known mammal’s fertility biology, captured relevant transcription factors for TNB biology and pointing out different sets of candidate genes for TNB in different environments. These findings may have important implication for animal production, as optimal breeding may vary depending on later environments. Based on these results, genomic diversity was identified and inferred across environments highlighting differential genetic control in each scenario.
dc.formatpdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherMammalian Genome
dc.relationVolume 28, Issue 9–10, Pages 426–435, October 2017
dc.rightsSpringer US
dc.subjectGene networks
dc.subjectPigs
dc.subjectAcross divergent environments
dc.titleGene networks for total number born in pigs across divergent environments
dc.typeArtigo


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