Long-term orange juice consumption is associated with low LDL-cholesterol and apolipoprotein B in normal and moderately hypercholesterolemic subjects

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorAptekmann, Nancy P.
dc.creatorCésar, Thaís Borges
dc.date2014-05-27T11:30:09Z
dc.date2016-10-25T18:52:35Z
dc.date2014-05-27T11:30:09Z
dc.date2016-10-25T18:52:35Z
dc.date2013-08-13
dc.date.accessioned2017-04-06T02:34:25Z
dc.date.available2017-04-06T02:34:25Z
dc.identifierLipids in Health and Disease, v. 12, n. 1, 2013.
dc.identifier1476-511X
dc.identifierhttp://hdl.handle.net/11449/76259
dc.identifierhttp://acervodigital.unesp.br/handle/11449/76259
dc.identifier10.1186/1476-511X-12-119
dc.identifierWOS:000323073500001
dc.identifier2-s2.0-84881129359.pdf
dc.identifier2-s2.0-84881129359
dc.identifierhttp://dx.doi.org/10.1186/1476-511X-12-119
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/896960
dc.descriptionAbstract. Background: This study investigated the hypothesis that long-term orange juice consumption (≥ 12 months) was associated with low risk factors for cardiovascular disease in adult men and women with normal and moderately high cholesterol blood levels. Methods. The sample consisted of 103 men (18-66 y) and 26 women (18-65 y); all were employees of an orange juice factory with daily access to free orange juice. The results showed that 41% of the individuals consumed 2 cups (480 mL) of orange juice per day for at least twelve months, while 59% of the volunteers are non-consumers of orange juice. Results: Orange juice consumers with normal serum lipid levels had significantly lower total cholesterol (-11%, p <0.001), LDL-cholesterol (-18%, p < 0.001), apolipoprotein B (apo B) (-12%, p < 0.01) and LDL/HDL ratio (-12%, p < 0.04) in comparison to non-consumers, as did the consumers with moderate hypercholesterolemia: lower total cholesterol (-5%, p <0.02), LDL-cholesterol (-12%, p <0.03), apolipoprotein B (-12%, p <0.01) and LDL/HDL ratio (-16%, p <0.05) in comparison the non-consumers counterparts. Serum levels of homocysteine, HDL- cholesterol and apolipoprotein A-1, body composition and the dietary intake of food energy and macronutrients did not differ among orange juice consumers and non-consumers, but vitamin C and folate intake was higher in orange juice consumers. Conclusion: Long-term orange juice consumers had lower levels of total cholesterol, LDL-cholesterol, apo B and LDL/HDL ratio and an improvement of folate and vitamin C in their diet. © 2013 Aptekmann and Cesar; licensee BioMed Central Ltd.
dc.languageeng
dc.relationLipids in Health and Disease
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectApo B
dc.subjectHomocisteína
dc.subjectHomocysteine
dc.subjectHumanos
dc.subjectHumans
dc.subjectLDL-cholesterol
dc.subjectOrange juice
dc.subjectSuco de laranja LDL-colesterol
dc.subjectapolipoprotein A1
dc.subjectapolipoprotein B
dc.subjectascorbic acid
dc.subjectcarbohydrate
dc.subjectfolic acid
dc.subjecthigh density lipoprotein cholesterol
dc.subjecthomocysteine
dc.subjectlow density lipoprotein cholesterol
dc.subjectsaturated fatty acid
dc.subjectadult
dc.subjectaged
dc.subjectbody composition
dc.subjectcaloric intake
dc.subjectcarbohydrate intake
dc.subjectcholesterol blood level
dc.subjectcontrolled study
dc.subjectfat intake
dc.subjectfemale
dc.subjectfood intake
dc.subjecthuman
dc.subjecthuman tissue
dc.subjecthypercholesterolemia
dc.subjectmacronutrient
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectorange juice
dc.titleLong-term orange juice consumption is associated with low LDL-cholesterol and apolipoprotein B in normal and moderately hypercholesterolemic subjects
dc.typeOtro


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