Interaction between mesenchymal stem cells and Ti-30Ta alloy after surface treatment

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorCapellato, Patricia
dc.creatorEscada, Ana L. A.
dc.creatorPopat, Ketul C.
dc.creatorClaro, Ana P. R. Alves
dc.date2014-05-27T11:30:09Z
dc.date2016-10-25T18:52:35Z
dc.date2014-05-27T11:30:09Z
dc.date2016-10-25T18:52:35Z
dc.date2013-08-13
dc.date.accessioned2017-04-06T02:34:22Z
dc.date.available2017-04-06T02:34:22Z
dc.identifierJournal of Biomedical Materials Research - Part A.
dc.identifier1549-3296
dc.identifier1552-4965
dc.identifierhttp://hdl.handle.net/11449/76254
dc.identifierhttp://acervodigital.unesp.br/handle/11449/76254
dc.identifier10.1002/jbm.a.34891
dc.identifierWOS:000337570400010
dc.identifier2-s2.0-84881150399
dc.identifierhttp://dx.doi.org/10.1002/jbm.a.34891
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/896955
dc.descriptionIn this study, in vitro cytocompatibility was investigated in the Ti-30Ta alloy after two kinds of surfaces treatments: alkaline and biomimetic treatment. Each condition was evaluated by scanning electron microscopy/energy-dispersive X-ray spectroscopy. Cellular adhesion, viability, protein expression, morphology, and differentiation were evaluated with Bone marrow stromal cells (MSCs) to investigate the short and long-term cellular response by fluorescence microscope imaging and colorimetric assays techniques. Two treatments exhibited similar results with respect to total protein content and enzyme activity as compared with alloy without treatment. However, it was observed improved of the biomineralization, bone matrix formation, enzyme activity, and MSCs functionality after biomimetic treatment. These results indicate that the biomimetic surface treatment has a high potential for enhanced osseointegration. © 2013 Wiley Periodicals, Inc.
dc.languageeng
dc.relationJournal of Biomedical Materials Research - Part A
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAlkali treatment
dc.subjectBiocompatibility
dc.subjectBiomimetic treatment
dc.subjectBone marrow stromal cells
dc.subjectTi-30Ta alloy
dc.titleInteraction between mesenchymal stem cells and Ti-30Ta alloy after surface treatment
dc.typeOtro


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